Tissue expression of CYP2J2 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	CYP2J2
Gene description	Cytochrome P450, family 2, subfamily J, polypeptide 2
Protein class	Enzymes Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (liver, small intestine)
GTEx:	Tissue enhanced (heart muscle)
FANTOM5:	Tissue enhanced (liver, small intestine)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (liver, small intestine)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (heart muscle)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (liver, small intestine)

GENE INFORMATION
Gene name	CYP2J2
Synonyms
Description	Cytochrome P450, family 2, subfamily J, polypeptide 2 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is thought to be the predominant enzyme responsible for epoxidation of endogenous arachidonic acid in cardiac tissue. [provided by RefSeq, Jul 2008]
Chromosome	1
Cytoband	p32.1
Chromosome location (bp)	59893308 - 59926790
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000134716 (version 83.38)
Entrez gene	1573
UniProt	P51589 (UniProt - Evidence at protein level)
neXtProt	NX_P51589
Antibodypedia	CYP2J2 antibodies

PROTEIN BROWSER

CYP2J2-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CYP2J2-001 ENSP00000360247 ENST00000371204	P51589 [Direct mapping] Cytochrome P450 2J2 Show all	Enzymes ENZYME proteins Oxidoreductases MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005506 [iron ion binding] GO:0005737 [cytoplasm] GO:0005789 [endoplasmic reticulum membrane] GO:0006690 [icosanoid metabolic process] GO:0006805 [xenobiotic metabolic process] GO:0008016 [regulation of heart contraction] GO:0008392 [arachidonic acid epoxygenase activity] GO:0008395 [steroid hydroxylase activity] GO:0008404 [arachidonic acid 14,15-epoxygenase activity] GO:0008405 [arachidonic acid 11,12-epoxygenase activity] GO:0016705 [oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen] GO:0016712 [oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen] GO:0019369 [arachidonic acid metabolic process] GO:0019373 [epoxygenase P450 pathway] GO:0019825 [oxygen binding] GO:0020037 [heme binding] GO:0042738 [exogenous drug catabolic process] GO:0043231 [intracellular membrane-bounded organelle] GO:0043651 [linoleic acid metabolic process] GO:0044281 [small molecule metabolic process] GO:0055114 [oxidation-reduction process] GO:0070062 [extracellular exosome] GO:0070330 [aromatase activity] GO:0071614 [linoleic acid epoxygenase activity] Show all	502 aa 57.6 kDa	Yes	0