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METTL5

GENERAL INFORMATION

Gene name

 METTL5

Gene description

 Methyltransferase like 5

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 10
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in most tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Pending external verification.

Reliability score

 Uncertain based on 1 antibody.
HPA038223
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 METTL5 (HGNC Symbol)

Synonyms

 HSPC133

Description

 Methyltransferase like 5 (HGNC Symbol)

Entrez gene summary

Chromosome

 2

Cytoband

 q31.1

Chromosome location (bp)

 169810081 - 169824931

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000138382 (version 83.38)

Entrez gene

 29081

UniProt

 Q9NRN9 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9NRN9

Antibodypedia

 METTL5 antibodies

PROTEIN BROWSER
METTL5-001
METTL5-002
METTL5-003
METTL5-004
METTL5-005
METTL5-006
METTL5-008
METTL5-010
METTL5-011
METTL5-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
METTL5-001
ENSP00000260953
ENST00000260953
Q9NRN9 [Direct mapping]
Methyltransferase-like protein 5
Show all
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003676 [nucleic acid binding]
GO:0008168 [methyltransferase activity]
GO:0032259 [methylation]
Show all
 209 aa
23.7 kDa 		No 0
METTL5-002
ENSP00000376415
ENST00000392640
Q9NRN9 [Direct mapping]
Methyltransferase-like protein 5
Show all
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003676 [nucleic acid binding]
GO:0008168 [methyltransferase activity]
GO:0032259 [methylation]
Show all
 209 aa
23.7 kDa 		No 0
METTL5-003
ENSP00000386582
ENST00000409965
Q9NRN9 [Direct mapping]
Methyltransferase-like protein 5
Show all
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003676 [nucleic acid binding]
GO:0008168 [methyltransferase activity]
GO:0032259 [methylation]
Show all
 209 aa
23.7 kDa 		No 0
METTL5-004
ENSP00000387056
ENST00000410097
B8ZZC8 [Direct mapping]
Methyltransferase-like protein 5
Show all
   Phobius predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003676 [nucleic acid binding]
GO:0008168 [methyltransferase activity]
GO:0032259 [methylation]
Show all
 244 aa
27.8 kDa 		No 0
METTL5-005
ENSP00000386703
ENST00000409837
B8ZZE3 [Direct mapping]
Methyltransferase like 5, isoform CRA_b; Methyltransferase-like protein 5
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   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003676 [nucleic acid binding]
GO:0008168 [methyltransferase activity]
GO:0032259 [methylation]
Show all
 198 aa
22.4 kDa 		No 0
METTL5-006
ENSP00000387106
ENST00000409340
B8ZZY8 [Direct mapping]
Methyltransferase-like protein 5
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 110 aa
12.9 kDa 		No 0
METTL5-008
ENSP00000395792
ENST00000442181
H7C0M7 [Direct mapping]
Methyltransferase-like protein 5
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003676 [nucleic acid binding]
GO:0008168 [methyltransferase activity]
GO:0032259 [methylation]
Show all
 126 aa
14.4 kDa 		No 0
METTL5-010
ENSP00000307903
ENST00000308099
E7EMN2 [Direct mapping]
Methyltransferase-like protein 5
Show all
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003676 [nucleic acid binding]
GO:0008168 [methyltransferase activity]
GO:0032259 [methylation]
Show all
 164 aa
18.6 kDa 		No 0
METTL5-011
ENSP00000444989
ENST00000538491
F5H4E8 [Direct mapping]
Methyltransferase-like protein 5
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 48 aa
5.8 kDa 		No 0
METTL5-201
ENSP00000479765
ENST00000614043
A0A087WVY0 [Direct mapping]
Methyltransferase-like protein 5
Show all
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 132 aa
15.1 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.