Fields »
ABOUT
HELP
BLOG
SHROOM3

GENERAL INFORMATION

Gene name

 SHROOM3

Gene description

 Shroom family member 3

Protein class

 Plasma proteins
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
GTEx:Mixed
FANTOM5:Tissue enhanced (small intestine)

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic and membranous expression in several tissues, most abundant in gastrointestinal tract.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Pending external verification.

Reliability score

 Supported based on 1 antibody.
HPA047784
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (small intestine)

GENE INFORMATION

Gene name

 SHROOM3 (HGNC Symbol)

Synonyms

 APXL3, KIAA1481, SHRM, ShrmL

Description

 Shroom family member 3 (HGNC Symbol)

Entrez gene summary

 This gene encodes a PDZ-domain-containing protein that belongs to a family of Shroom-related proteins. This protein may be involved in regulating cell shape in certain tissues. A similar protein in mice is required for proper neurulation. [provided by RefSeq, Jan 2011]

Chromosome

 4

Cytoband

 q21.1

Chromosome location (bp)

 76435100 - 76783253

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000138771 (version 83.38)

Entrez gene

 57619

UniProt

 Q8TF72 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8TF72

Antibodypedia

 SHROOM3 antibodies

PROTEIN BROWSER
SHROOM3-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SHROOM3-001
ENSP00000296043
ENST00000296043
Q8TF72 [Direct mapping]
Protein Shroom3
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000902 [cell morphogenesis]
GO:0001843 [neural tube closure]
GO:0002066 [columnar/cuboidal epithelial cell development]
GO:0003779 [actin binding]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005856 [cytoskeleton]
GO:0005874 [microtubule]
GO:0005912 [adherens junction]
GO:0007389 [pattern specification process]
GO:0008360 [regulation of cell shape]
GO:0016324 [apical plasma membrane]
GO:0030036 [actin cytoskeleton organization]
GO:0043296 [apical junction complex]
GO:0043482 [cellular pigment accumulation]
GO:0045176 [apical protein localization]
GO:0045177 [apical part of cell]
GO:0051015 [actin filament binding]
Show all
 1996 aa
216.9 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.