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ZCRB1

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GENERAL INFORMATION

Gene name

 ZCRB1

Gene description

 Zinc finger CCHC-type and RNA binding motif 1

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

Summary

RNA cell category

 Expressed in all

Protein evidence

 Evidence at protein level

Main location

 Not available

DATA RELIABILITY

Reliability score

 Pending cell analysis.

ASSAYS
RNA expression

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

GENE INFORMATION

Gene name

 ZCRB1 (HGNC Symbol)

Synonyms

 MADP-1, MADP1, RBM36, SNRNP31, ZCCHC19

Description

 Zinc finger CCHC-type and RNA binding motif 1 (HGNC Symbol)

Entrez gene summary

 Pre-mRNA splicing is catalyzed by the spliceosome. U12-type spliceosome binds U12-type pre-mRNAs and recognizes the 5' splice site and branch-point sequence. U11 and U12 snRNPs are components of U12-type spliceosome and function as a molecular bridge connecting both ends of the intron. The protein encoded by this gene contains a RNA recognition motif. It was identified as one of the protein components of U11/U12 snRNPs. This protein and many other U11/U12 snRNP proteins are highly conserved in organisms known to contain U12-type introns. These proteins have been shown to be essential for cell viability, suggesting the key roles in U12-type splicing. [provided by RefSeq, Jul 2008]

Chromosome

 12

Cytoband

 q12

Chromosome location (bp)

 42312078 - 42326118

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000139168 (version 83.38)

Entrez gene

 85437

UniProt

 Q8TBF4 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8TBF4

Antibodypedia

 ZCRB1 antibodies

PROTEIN BROWSER
ZCRB1-001
ZCRB1-002
ZCRB1-005

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ZCRB1-001
ENSP00000266529
ENST00000266529
Q8TBF4 [Direct mapping]
Zinc finger CCHC-type and RNA-binding motif-containing protein 1
A0A024R106 [Target identity:100%; Query identity:100%]
Zinc finger CCHC-type and RNA binding motif 1, isoform CRA_a
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0000398 [mRNA splicing, via spliceosome]
GO:0003676 [nucleic acid binding]
GO:0005654 [nucleoplasm]
GO:0005689 [U12-type spliceosomal complex]
GO:0008270 [zinc ion binding]
GO:0008380 [RNA splicing]
GO:0010467 [gene expression]
GO:0044822 [poly(A) RNA binding]
Show all
 217 aa
24.6 kDa 		No 0
ZCRB1-002
ENSP00000448780
ENST00000552235
F8VXY6 [Direct mapping]
Zinc finger CCHC-type and RNA-binding motif-containing protein 1
Show all
   Phobius predicted secreted proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0003676 [nucleic acid binding]
GO:0008270 [zinc ion binding]
Show all
 133 aa
15.1 kDa 		No 0
ZCRB1-005
ENSP00000446732
ENST00000552673
G3V1V1 [Direct mapping]
Zinc finger CCHC-type and RNA binding motif 1, isoform CRA_b; Zinc finger CCHC-type and RNA-binding motif-containing protein 1
Show all
   Phobius predicted secreted proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0003676 [nucleic acid binding]
GO:0008270 [zinc ion binding]
Show all
 176 aa
20.1 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.