Cell atlas - ANP32D - The Human Protein Atlas

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ANP32D

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Centrosome
	Cytosol
	Nucleoplasm

Human cell
	Centrosome
	Cytosol
	Nucleoplasm

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GENERAL INFORMATION
Gene name	ANP32D
Gene description	Acidic (leucine-rich) nuclear phosphoprotein 32 family, member D
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the cytosol, centrosome & nucleoplasm. Caution: Based on antibodies targeting proteins from multiple genes.
RNA cell category	Not detected
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (approved), Centrosome (approved), Cytosol (approved)

DATA RELIABILITY
Reliability score	Approved based on 2 antibodies. HPA063133 , HPA067561
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ASSAYS

RNA expression

Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Not detected Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the cytosol, centrosome & nucleoplasm. Caution: Based on antibodies targeting proteins from multiple genes.

Main location

Nucleoplasm (approved), Centrosome (approved), Cytosol (approved)


	Toggle channels	Low High G1 S G2 M N/A

Antibody	Cell line	Location
HPA063133	MCF7	Nucleoplasm
HPA063133	MCF7	Cytosol
HPA063133	RH-30	Nucleoplasm
		Centrosome
		Cytosol
HPA063133	U-2 OS	Nucleoplasm
HPA063133	U-2 OS	Centrosome
HPA067561	HEK 293	Nucleoplasm
HPA067561	SK-MEL-30	Nucleoplasm
HPA067561	SK-MEL-30	Centrosome
HPA067561	U-2 OS	Nucleoplasm

GENE INFORMATION
Gene name	ANP32D (HGNC Symbol)
Synonyms	PP32R2
Description	Acidic (leucine-rich) nuclear phosphoprotein 32 family, member D (HGNC Symbol)
Entrez gene summary	Phosphoprotein 32 (PP32) is a tumor suppressor that can inhibit several types of cancers, including prostate and breast cancers. The protein encoded by this gene is one of at least two proteins that are similar in amino acid sequence to PP32 and are part of the same acidic nuclear phosphoprotein gene family. However, unlike PP32, the encoded protein is tumorigenic. The tumor suppressor function of PP32 has been localized to a 25 amino acid region that is absent in the protein encoded by this gene. This gene does not contain introns. [provided by RefSeq, Jul 2008]
Chromosome	12
Cytoband	q13.11
Chromosome location (bp)	48472665 - 48473624
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000139223 (version 83.38)
Entrez gene	23519
UniProt	O95626 (UniProt - Evidence at transcript level)
neXtProt	NX_O95626
Antibodypedia	ANP32D antibodies

PROTEIN BROWSER

ANP32D-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ANP32D-001 ENSP00000266594 ENST00000266594	O95626 [Direct mapping] Acidic leucine-rich nuclear phosphoprotein 32 family member D Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] Show all	131 aa 14.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.