Expression of ANP32D in cancer - Summary - The Human Protein Atlas

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ANP32D

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	ANP32D
Gene description	Acidic (leucine-rich) nuclear phosphoprotein 32 family, member D
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Not detected
HPA (normal tissue):	Not detected

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. No RNA expression data detected and pending external verification. Caution, targets protein from more than one gene.
Reliability score	Uncertain based on 2 antibodies. HPA063133 , HPA067561
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA063133	HPA067561

GENE INFORMATION
Gene name	ANP32D (HGNC Symbol)
Synonyms	PP32R2
Description	Acidic (leucine-rich) nuclear phosphoprotein 32 family, member D (HGNC Symbol)
Entrez gene summary	Phosphoprotein 32 (PP32) is a tumor suppressor that can inhibit several types of cancers, including prostate and breast cancers. The protein encoded by this gene is one of at least two proteins that are similar in amino acid sequence to PP32 and are part of the same acidic nuclear phosphoprotein gene family. However, unlike PP32, the encoded protein is tumorigenic. The tumor suppressor function of PP32 has been localized to a 25 amino acid region that is absent in the protein encoded by this gene. This gene does not contain introns. [provided by RefSeq, Jul 2008]
Chromosome	12
Cytoband	q13.11
Chromosome location (bp)	48472665 - 48473624
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000139223 (version 83.38)
Entrez gene	23519
UniProt	O95626 (UniProt - Evidence at transcript level)
neXtProt	NX_O95626
Antibodypedia	ANP32D antibodies

PROTEIN BROWSER

ANP32D-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ANP32D-001 ENSP00000266594 ENST00000266594	O95626 [Direct mapping] Acidic leucine-rich nuclear phosphoprotein 32 family member D Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] Show all	131 aa 14.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.