Cell atlas - GLTP - The Human Protein Atlas

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GLTP

TISSUE

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CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS MOUSE CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol

Human cell
	Cytosol

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GENERAL INFORMATION
Gene name	GLTP
Gene description	Glycolipid transfer protein
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the cytosol.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Cytosol (supported)
Mouse	Localized to the Cytosol in mouse cells.

DATA RELIABILITY
Reliability score	Supported based on 1 antibody. HPA056461
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the cytosol.

Main location

Cytosol (supported)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA056461	MCF7	No staining
	HPA056461	PC-3	Cytosol
	HPA056461	U-2 OS	No staining

MOUSE CELLS

Main location

Cytosol

Mouse gene

ENSMUSG00000011884 (version 83)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location
	HPA056461	NIH 3T3	Cytosol

GENE INFORMATION
Gene name	GLTP
Synonyms
Description	Glycolipid transfer protein (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is similar to bovine and porcine proteins which accelerate transfer of certain glycosphingolipids and glyceroglycolipids between membranes. It is thought to be a cytoplasmic protein. [provided by RefSeq, Jul 2008]
Chromosome	12
Cytoband	q24.11
Chromosome location (bp)	109850943 - 109880488
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000139433 (version 83.38)
Entrez gene	51228
UniProt	Q9NZD2 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NZD2
Antibodypedia	GLTP antibodies

PROTEIN BROWSER

GLTP-001	GLTP-004	GLTP-005	GLTP-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GLTP-001 ENSP00000315263 ENST00000318348	Q9NZD2 [Direct mapping] Glycolipid transfer protein A0A024RBI7 [Target identity:100%; Query identity:100%] Glycolipid transfer protein, isoform CRA_a Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0006665 [sphingolipid metabolic process] GO:0006687 [glycosphingolipid metabolic process] GO:0008289 [lipid binding] GO:0016020 [membrane] GO:0017089 [glycolipid transporter activity] GO:0044281 [small molecule metabolic process] GO:0046836 [glycolipid transport] GO:0051861 [glycolipid binding] GO:0070062 [extracellular exosome] Show all	209 aa 23.8 kDa	No	0
GLTP-004 ENSP00000445919 ENST00000544393	F5H0U5 [Direct mapping] Glycolipid transfer protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005737 [cytoplasm] GO:0017089 [glycolipid transporter activity] GO:0046836 [glycolipid transport] GO:0051861 [glycolipid binding] Show all	190 aa 21.7 kDa	No	0
GLTP-005 ENSP00000440136 ENST00000540772	H0YFS9 [Direct mapping] Glycolipid transfer protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005737 [cytoplasm] GO:0017089 [glycolipid transporter activity] GO:0046836 [glycolipid transport] GO:0051861 [glycolipid binding] Show all	183 aa 20.7 kDa	No	0
GLTP-201 ENSP00000481582 ENST00000617457	F5GZ49 [Direct mapping] Glycolipid transfer protein; Glycolipid transfer protein isoform 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005737 [cytoplasm] GO:0017089 [glycolipid transporter activity] GO:0046836 [glycolipid transport] GO:0051861 [glycolipid binding] Show all	67 aa 7.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.