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FITM1

GENERAL INFORMATION

Gene name

 FITM1

Gene description

 Fat storage-inducing transmembrane protein 1

Protein class

 Predicted membrane proteins

Predicted localization

 Membrane

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Group enriched (heart muscle, skeletal muscle)
GTEx:Group enriched (heart muscle, skeletal muscle)
FANTOM5:Tissue enhanced (heart muscle, skeletal muscle)

Protein evidence

 Evidence at protein level

Protein expression

 General cytoplasmic expression

DATA RELIABILITY

Data reliability
description

 Antibody staining not consistent with RNA expression data.

Reliability score

 Uncertain based on 1 antibody.
HPA019842
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Skeletal muscle

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (heart muscle, skeletal muscle)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (heart muscle, skeletal muscle)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (heart muscle, skeletal muscle)

GENE INFORMATION

Gene name

 FITM1 (HGNC Symbol)

Synonyms

 FIT1

Description

 Fat storage-inducing transmembrane protein 1 (HGNC Symbol)

Entrez gene summary

 FIT1 belongs to an evolutionarily conserved family of proteins involved in fat storage (Kadereit et al., 2008 [PubMed 18160536]).[supplied by OMIM, May 2008]

Chromosome

 14

Cytoband

 q12

Chromosome location (bp)

 24131275 - 24132849

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000139914 (version 83.38)

Entrez gene

 161247

UniProt

 A5D6W6 (UniProt - Evidence at transcript level)

neXtProt

 NX_A5D6W6

Antibodypedia

 FITM1 antibodies

PROTEIN BROWSER
FITM1-001
FITM1-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
FITM1-001
ENSP00000267426
ENST00000267426
A5D6W6 [Direct mapping]
Fat storage-inducing transmembrane protein 1
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Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   6TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Show all
GO:0003674 [molecular_function]
GO:0005789 [endoplasmic reticulum membrane]
GO:0008654 [phospholipid biosynthetic process]
GO:0010890 [positive regulation of sequestering of triglyceride]
GO:0019915 [lipid storage]
GO:0030176 [integral component of endoplasmic reticulum membrane]
GO:0034389 [lipid particle organization]
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 292 aa
32.2 kDa 		No 6
FITM1-002
ENSP00000453741
ENST00000559294
A5D6W6 [Direct mapping]
Fat storage-inducing transmembrane protein 1
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   2TM proteins predicted by MDM
Show all
GO:0003674 [molecular_function]
GO:0005789 [endoplasmic reticulum membrane]
GO:0008654 [phospholipid biosynthetic process]
GO:0010890 [positive regulation of sequestering of triglyceride]
GO:0019915 [lipid storage]
GO:0030176 [integral component of endoplasmic reticulum membrane]
GO:0034389 [lipid particle organization]
Show all
 96 aa
10.8 kDa 		No 2

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.