Tissue expression of TICRR - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	TICRR
Gene description	TOPBP1-interacting checkpoint and replication regulator
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Mixed
GTEx:	Tissue enhanced (esophagus)
FANTOM5:	Tissue enhanced (testis, tonsil)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Mixed
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (esophagus)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (testis, tonsil)

GENE INFORMATION
Gene name	TICRR (HGNC Symbol)
Synonyms	C15orf42, FLJ41618, MGC45866, SLD3, Treslin
Description	TOPBP1-interacting checkpoint and replication regulator (HGNC Symbol)
Entrez gene summary	Treslin is involved in the initiation of DNA replication (Kumagai et al., 2010 [PubMed 20116089]).[supplied by OMIM, Apr 2010]
Chromosome	15
Cytoband	q26.1
Chromosome location (bp)	89575482 - 89631056
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000140534 (version 83.38)
Entrez gene	90381
UniProt	Q7Z2Z1 (UniProt - Evidence at protein level)
neXtProt	NX_Q7Z2Z1
Antibodypedia	TICRR antibodies

PROTEIN BROWSER

TICRR-001	TICRR-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TICRR-001 ENSP00000268138 ENST00000268138	Q7Z2Z1 [Direct mapping] Treslin Show all	SPOCTOPUS predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000075 [cell cycle checkpoint] GO:0001731 [formation of translation preinitiation complex] GO:0003682 [chromatin binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0006260 [DNA replication] GO:0006281 [DNA repair] GO:0010212 [response to ionizing radiation] GO:0030174 [regulation of DNA-dependent DNA replication initiation] GO:0033314 [mitotic DNA replication checkpoint] Show all	1910 aa 210.9 kDa	No	0
TICRR-003 ENSP00000453306 ENST00000560985	Q7Z2Z1 [Direct mapping] Treslin Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000075 [cell cycle checkpoint] GO:0001731 [formation of translation preinitiation complex] GO:0003682 [chromatin binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0006260 [DNA replication] GO:0006281 [DNA repair] GO:0010212 [response to ionizing radiation] GO:0030174 [regulation of DNA-dependent DNA replication initiation] GO:0033314 [mitotic DNA replication checkpoint] Show all	1909 aa 210.8 kDa	No	0