Fields »
ABOUT
HELP
BLOG
SH3GL3

GENERAL INFORMATION

Gene name

 SH3GL3

Gene description

 SH3-domain GRB2-like 3

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Group enriched (cerebral cortex, testis)
GTEx:Group enriched (caudate, cerebellum, cerebral cortex, hippocampus, hypothalamus, testis)
FANTOM5:Group enriched (brain, caudate, cerebellum, hippocampus, testis)

Protein evidence

 Evidence at protein level

Protein expression

 Selective expression in brain and testis

DATA RELIABILITY

Data reliability
description

 Antibody staining consistent with RNA expression data.

Reliability score

 Supported based on 1 antibody.
HPA039381
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (cerebral cortex, testis)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (caudate, cerebellum, cerebral cortex, hippocampus, hypothalamus, testis)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (brain, caudate, cerebellum, hippocampus, testis)

GENE INFORMATION

Gene name

 SH3GL3 (HGNC Symbol)

Synonyms

 CNSA3, EEN-B2, HsT19371, SH3D2C, SH3P13

Description

 SH3-domain GRB2-like 3 (HGNC Symbol)

Entrez gene summary

Chromosome

 15

Cytoband

 q25.2

Chromosome location (bp)

 83447228 - 83618743

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000140600 (version 83.38)

Entrez gene

 6457

UniProt

 Q99963 (UniProt - Evidence at protein level)

neXtProt

 NX_Q99963

Antibodypedia

 SH3GL3 antibodies

PROTEIN BROWSER
SH3GL3-001
SH3GL3-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SH3GL3-001
ENSP00000320092
ENST00000324537
Q99963 [Direct mapping]
Endophilin-A3
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005769 [early endosome]
GO:0006897 [endocytosis]
GO:0007165 [signal transduction]
GO:0007417 [central nervous system development]
GO:0008289 [lipid binding]
GO:0031901 [early endosome membrane]
GO:0042802 [identical protein binding]
GO:0070062 [extracellular exosome]
Show all
 355 aa
40.2 kDa 		No 0
SH3GL3-002
ENSP00000391372
ENST00000427482
Q99963 [Direct mapping]
Endophilin-A3
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0006897 [endocytosis]
GO:0007165 [signal transduction]
GO:0007417 [central nervous system development]
GO:0008289 [lipid binding]
GO:0031901 [early endosome membrane]
GO:0042802 [identical protein binding]
GO:0070062 [extracellular exosome]
Show all
 347 aa
39.3 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.