Expression of C16orf58 in cancer - Summary - The Human Protein Atlas

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C16orf58

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	C16orf58
Gene description	Chromosome 16 open reading frame 58
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in selected tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA024406
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA024406

GENE INFORMATION
Gene name	C16orf58 (HGNC Symbol)
Synonyms	FLJ13868
Description	Chromosome 16 open reading frame 58 (HGNC Symbol)
Entrez gene summary	This gene encodes a putative transmembrane protein containing a conserved DUF647 domain that may be involved in protein-protein interaction. The encoded protein is related to a plant protein that participates in ultraviolet B light-sensing during root morphogenesis. [provided by RefSeq, Feb 2013]
Chromosome	16
Cytoband	p11.2
Chromosome location (bp)	31489471 - 31509309
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000140688 (version 83.38)
Entrez gene	64755
UniProt	Q96GQ5 (UniProt - Evidence at protein level)
neXtProt	NX_Q96GQ5
Antibodypedia	C16orf58 antibodies

PROTEIN BROWSER

C16orf58-001	C16orf58-002	C16orf58-004	C16orf58-007	C16orf58-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C16orf58-001 ENSP00000317579 ENST00000327237	Q96GQ5 [Direct mapping] RUS1 family protein C16orf58 A0A024QZE6 [Target identity:100%; Query identity:100%] Chromosome 16 open reading frame 58, isoform CRA_a Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0016020 [membrane] GO:0016021 [integral component of membrane] Show all	468 aa 51 kDa	No	3
C16orf58-002 ENSP00000456050 ENST00000567994	H3BR29 [Direct mapping] RUS1 family protein C16orf58 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	423 aa 46.3 kDa	No	3
C16orf58-004 ENSP00000456775 ENST00000570164	H3BSM7 [Direct mapping] RUS1 family protein C16orf58 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	466 aa 50.8 kDa	No	2
C16orf58-007 ENSP00000459952 ENST00000564807	I3L2V0 [Direct mapping] RUS1 family protein C16orf58 Show all	MEMSAT3 predicted membrane proteins THUMBUP predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		82 aa 9.1 kDa	No	0
C16orf58-201 ENSP00000398074 ENST00000430477	Q96GQ5 [Direct mapping] RUS1 family protein C16orf58 A0A024QZE6 [Target identity:100%; Query identity:100%] Chromosome 16 open reading frame 58, isoform CRA_a Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016020 [membrane] GO:0016021 [integral component of membrane] Show all	468 aa 51 kDa	No	4

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.