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Cell lines sorted after organ of phenotypic resemblance.
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GENE INFORMATION
Gene name
ABCC12 (HGNC Symbol)
Synonyms
MRP9
Description
ATP-binding cassette, sub-family C (CFTR/MRP), member 12 (HGNC Symbol)
Entrez gene summary
This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer. [provided by RefSeq, Jul 2008]
E9PHY2 [Direct mapping] Multidrug resistance-associated protein 9
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Predicted intracellular proteins
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GO:0005524 [ATP binding] GO:0016021 [integral component of membrane] GO:0042626 [ATPase activity, coupled to transmembrane movement of substances] GO:0055085 [transmembrane transport]
