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KSR1

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GENERAL INFORMATION

Gene name

 KSR1

Gene description

 Kinase suppressor of ras 1

Protein class

 Enzymes
Predicted intracellular proteins
RAS pathway related proteins

Predicted localization

 Intracellular

Number of transcripts

 9
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

Summary

RNA cell category

 Cell line enhanced (HDLM-2, HEL)

Protein evidence

 Evidence at protein level

Main location

 Not available

DATA RELIABILITY

Reliability score

 Pending cell analysis.

ASSAYS
RNA expression

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (HDLM-2, HEL)
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

GENE INFORMATION

Gene name

 KSR1 (HGNC Symbol)

Synonyms

 KSR, RSU2

Description

 Kinase suppressor of ras 1 (HGNC Symbol)

Entrez gene summary

Chromosome

 17

Cytoband

 q11.2

Chromosome location (bp)

 27456714 - 27626438

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000141068 (version 83.38)

Entrez gene

 8844

UniProt

 Q8IVT5 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8IVT5

Antibodypedia

 KSR1 antibodies

PROTEIN BROWSER
KSR1-001
KSR1-005
KSR1-007
KSR1-011
KSR1-012
KSR1-017
KSR1-019
KSR1-201
KSR1-202

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
KSR1-001
ENSP00000381958
ENST00000398988
Q8IVT5 [Direct mapping]
Kinase suppressor of Ras 1
Show all
Enzymes
   Kinases
   TKL Ser/Thr protein kinases
Predicted intracellular proteins
RAS pathway related proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000165 [MAPK cascade]
GO:0000186 [activation of MAPKK activity]
GO:0004672 [protein kinase activity]
GO:0005078 [MAP-kinase scaffold activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005783 [endoplasmic reticulum]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005829 [cytosol]
GO:0006468 [protein phosphorylation]
GO:0007173 [epidermal growth factor receptor signaling pathway]
GO:0007264 [small GTPase mediated signal transduction]
GO:0007265 [Ras protein signal transduction]
GO:0007411 [axon guidance]
GO:0008022 [protein C-terminus binding]
GO:0008286 [insulin receptor signaling pathway]
GO:0008543 [fibroblast growth factor receptor signaling pathway]
GO:0016020 [membrane]
GO:0031434 [mitogen-activated protein kinase kinase binding]
GO:0035556 [intracellular signal transduction]
GO:0038095 [Fc-epsilon receptor signaling pathway]
GO:0043234 [protein complex]
GO:0043410 [positive regulation of MAPK cascade]
GO:0045087 [innate immune response]
GO:0046872 [metal ion binding]
GO:0048010 [vascular endothelial growth factor receptor signaling pathway]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
Show all
 762 aa
84.7 kDa 		No 0
KSR1-005
ENSP00000463204
ENST00000580163
J3QKR8 [Direct mapping]
Kinase suppressor of Ras 1
Show all
Predicted intracellular proteins
RAS pathway related proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 46 aa
5.1 kDa 		No 0
KSR1-007
ENSP00000464081
ENST00000583370
J3QR75 [Direct mapping]
Kinase suppressor of Ras 1
Show all
Predicted intracellular proteins
RAS pathway related proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 155 aa
16.3 kDa 		No 0
KSR1-011
ENSP00000381952
ENST00000398982
A8MY87 [Direct mapping]
Kinase suppressor of Ras 1
Show all
Predicted intracellular proteins
RAS pathway related proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0005524 [ATP binding]
GO:0005622 [intracellular]
GO:0006468 [protein phosphorylation]
GO:0035556 [intracellular signal transduction]
Show all
 612 aa
69.1 kDa 		No 0
KSR1-012
ENSP00000464680
ENST00000582410
J3QSG8 [Direct mapping]
Kinase suppressor of Ras 1
Show all
Predicted intracellular proteins
RAS pathway related proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0005524 [ATP binding]
GO:0006468 [protein phosphorylation]
Show all
 113 aa
12.8 kDa 		No 0
KSR1-017
ENSP00000463790
ENST00000580430
J3QQL4 [Direct mapping]
Kinase suppressor of Ras 1
Show all
Predicted intracellular proteins
RAS pathway related proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0005524 [ATP binding]
GO:0006468 [protein phosphorylation]
Show all
 139 aa
15.7 kDa 		No 0
KSR1-019
ENSP00000463779
ENST00000578981
J3QQK5 [Direct mapping]
Kinase suppressor of Ras 1
Show all
   SPOCTOPUS predicted secreted proteins
Predicted intracellular proteins
RAS pathway related proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 130 aa
14.8 kDa 		No 0
KSR1-201
ENSP00000268763
ENST00000268763
A0A0A0MQW1 [Direct mapping]
Protein kinase C
Show all
Predicted intracellular proteins
RAS pathway related proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0004697 [protein kinase C activity]
GO:0005524 [ATP binding]
GO:0005622 [intracellular]
GO:0006468 [protein phosphorylation]
GO:0035556 [intracellular signal transduction]
GO:0046872 [metal ion binding]
Show all
 846 aa
94.4 kDa 		No 0
KSR1-202
ENSP00000438795
ENST00000509603
Q8IVT5 [Direct mapping]
Kinase suppressor of Ras 1
Show all
Enzymes
   Kinases
   TKL Ser/Thr protein kinases
Predicted intracellular proteins
RAS pathway related proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000165 [MAPK cascade]
GO:0000186 [activation of MAPKK activity]
GO:0004672 [protein kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005783 [endoplasmic reticulum]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005829 [cytosol]
GO:0006468 [protein phosphorylation]
GO:0007173 [epidermal growth factor receptor signaling pathway]
GO:0007264 [small GTPase mediated signal transduction]
GO:0007265 [Ras protein signal transduction]
GO:0007411 [axon guidance]
GO:0008022 [protein C-terminus binding]
GO:0008286 [insulin receptor signaling pathway]
GO:0008543 [fibroblast growth factor receptor signaling pathway]
GO:0016020 [membrane]
GO:0035556 [intracellular signal transduction]
GO:0038095 [Fc-epsilon receptor signaling pathway]
GO:0043234 [protein complex]
GO:0045087 [innate immune response]
GO:0046872 [metal ion binding]
GO:0048010 [vascular endothelial growth factor receptor signaling pathway]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
Show all
 762 aa
84.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.