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MVB12A

GENERAL INFORMATION

Gene name

 MVB12A

Gene description

 Multivesicular body subunit 12A

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 8
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic and membranous expression in most cell types.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Approved based on 2 antibodies.
HPA041885 , HPA042231
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 MVB12A (HGNC Symbol)

Synonyms

 FAM125A, FLJ32495

Description

 Multivesicular body subunit 12A (HGNC Symbol)

Entrez gene summary

Chromosome

 19

Cytoband

 p13.11

Chromosome location (bp)

 17405722 - 17433724

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000141971 (version 83.38)

Entrez gene

 93343

UniProt

 Q96EY5 (UniProt - Evidence at protein level)

neXtProt

 NX_Q96EY5

Antibodypedia

 MVB12A antibodies

PROTEIN BROWSER
MVB12A-001
MVB12A-007
MVB12A-008
MVB12A-009
MVB12A-012
MVB12A-016
MVB12A-017
MVB12A-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
MVB12A-001
ENSP00000324810
ENST00000317040
Q96EY5 [Direct mapping]
Multivesicular body subunit 12A
A0A024R7L6 [Target identity:100%; Query identity:100%]
Uncharacterized protein
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000813 [ESCRT I complex]
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005829 [cytosol]
GO:0008289 [lipid binding]
GO:0015031 [protein transport]
GO:0016235 [aggresome]
GO:0017124 [SH3 domain binding]
GO:0019075 [virus maturation]
GO:0031902 [late endosome membrane]
GO:0031982 [vesicle]
GO:0042058 [regulation of epidermal growth factor receptor signaling pathway]
GO:0043130 [ubiquitin binding]
GO:0043162 [ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0048524 [positive regulation of viral process]
GO:0070062 [extracellular exosome]
GO:1903772 [regulation of viral budding via host ESCRT complex]
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 273 aa
28.8 kDa 		No 0
MVB12A-007
ENSP00000433677
ENST00000528515
E9PJW8 [Direct mapping]
Multivesicular body subunit 12A
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   SPOCTOPUS predicted secreted proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 199 aa
20.8 kDa 		No 0
MVB12A-008
ENSP00000432526
ENST00000529939
E9PQA6 [Direct mapping]
Multivesicular body subunit 12A
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0016235 [aggresome]
GO:0043231 [intracellular membrane-bounded organelle]
Show all
 273 aa
28.7 kDa 		No 0
MVB12A-009
ENSP00000433280
ENST00000528911
E9PLL0 [Direct mapping]
Multivesicular body subunit 12A
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
Show all
 121 aa
13 kDa 		No 0
MVB12A-012
ENSP00000435052
ENST00000528604
E9PLZ8 [Direct mapping]
Multivesicular body subunit 12A
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 134 aa
14.4 kDa 		No 0
MVB12A-016
ENSP00000472288
ENST00000600514
E9PLL0 [Direct mapping]
Multivesicular body subunit 12A
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
Show all
 121 aa
13 kDa 		No 0
MVB12A-017
ENSP00000470611
ENST00000594784
M0QZK6 [Direct mapping]
Multivesicular body subunit 12A
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 122 aa
13.1 kDa 		No 0
MVB12A-201
ENSP00000444653
ENST00000543795
Q96EY5 [Direct mapping]
Multivesicular body subunit 12A
A0A024R7L6 [Target identity:100%; Query identity:100%]
Uncharacterized protein
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000813 [ESCRT I complex]
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005829 [cytosol]
GO:0008289 [lipid binding]
GO:0015031 [protein transport]
GO:0016235 [aggresome]
GO:0017124 [SH3 domain binding]
GO:0019075 [virus maturation]
GO:0031902 [late endosome membrane]
GO:0031982 [vesicle]
GO:0042058 [regulation of epidermal growth factor receptor signaling pathway]
GO:0043130 [ubiquitin binding]
GO:0043162 [ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0048524 [positive regulation of viral process]
GO:0070062 [extracellular exosome]
GO:1903772 [regulation of viral budding via host ESCRT complex]
Show all
 273 aa
28.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.