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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

Cancer

Prognosis

Category

Score

Score

Score

Antibodies

Column

 
 
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RGS16
  • TISSUE

  • CELL

  • PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

RGS16

Gene description

Regulator of G-protein signaling 16

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Tissue enriched (thyroid gland)
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in several tissues.

DATA RELIABILITY

Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Reliability score

Uncertain based on 2 antibodies.
HPA053250 , HPA055824
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Placenta

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (thyroid gland)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

RGS16 (HGNC Symbol)

Synonyms

A28-RGS14, RGS-r

Description

Regulator of G-protein signaling 16 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the 'regulator of G protein signaling' family. It inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits. It also may play a role in regulating the kinetics of signaling in the phototransduction cascade. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

q25.3

Chromosome location (bp)

182598623 - 182604408

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000143333 (version 83.38)

Entrez gene

6004

UniProt

O15492 (UniProt - Evidence at protein level)

neXtProt

NX_O15492

Antibodypedia

RGS16 antibodies

PROTEIN BROWSER

RGS16-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RGS16-001
ENSP00000356529
ENST00000367558
O15492 [Direct mapping]
Regulator of G-protein signaling 16
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Predicted intracellular proteins
Show all
GO:0005096 [GTPase activator activity]
GO:0005515 [protein binding]
GO:0005516 [calmodulin binding]
GO:0005737 [cytoplasm]
GO:0005886 [plasma membrane]
GO:0007601 [visual perception]
GO:0008277 [regulation of G-protein coupled receptor protein signaling pathway]
GO:0009968 [negative regulation of signal transduction]
GO:0043547 [positive regulation of GTPase activity]
GO:0045121 [membrane raft]
Show all
202 aa
22.7 kDa
No 0

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