Cell atlas - GOLPH3L - The Human Protein Atlas

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GOLPH3L

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Nucleoplasm
	Plasma membrane

Human cell
	Cytosol
	Nucleoplasm
	Plasma Membrane

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GENERAL INFORMATION
Gene name	GOLPH3L
Gene description	Golgi phosphoprotein 3-like
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the plasma membrane & cytosol. In addition localized to the nucleoplasm.
RNA cell category	Cell line enriched (U-698)
Protein evidence	Evidence at protein level
Main location	Localized to the Plasma membrane (approved), Cytosol (approved)
Additional location	In addition localized to the Nucleoplasm (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA028558
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enriched (U-698) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the plasma membrane & cytosol. In addition localized to the nucleoplasm.

Main location

Plasma membrane (approved), Cytosol (approved)

Additional location

Nucleoplasm (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA028558	A-431	Nucleoplasm
			Plasma membrane
			Cytosol
	HPA028558	U-2 OS	Nucleoplasm
			Plasma membrane
			Cytosol
	HPA028558	U-251 MG	Nucleoplasm
			Plasma membrane
			Cytosol

GENE INFORMATION
Gene name	GOLPH3L (HGNC Symbol)
Synonyms	GPP34R
Description	Golgi phosphoprotein 3-like (HGNC Symbol)
Entrez gene summary	The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is localized at the Golgi stack and may have a regulatory role in Golgi trafficking. [provided by RefSeq, Jul 2008]
Chromosome	1
Cytoband	q21.3
Chromosome location (bp)	150646225 - 150697144
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000143457 (version 83.38)
Entrez gene	55204
UniProt	Q9H4A5 (UniProt - Evidence at protein level)
neXtProt	NX_Q9H4A5
Antibodypedia	GOLPH3L antibodies

PROTEIN BROWSER

GOLPH3L-001	GOLPH3L-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GOLPH3L-001 ENSP00000271732 ENST00000271732	Q9H4A5 [Direct mapping] Golgi phosphoprotein 3-like Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0005515 [protein binding] GO:0007030 [Golgi organization] GO:0032580 [Golgi cisterna membrane] GO:0032588 [trans-Golgi network membrane] GO:0050714 [positive regulation of protein secretion] GO:0070273 [phosphatidylinositol-4-phosphate binding] Show all	285 aa 32.8 kDa	No	0
GOLPH3L-002 ENSP00000410476 ENST00000427665	Q5T5I6 [Direct mapping] Golgi phosphoprotein 3-like Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		269 aa 31.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.