Expression of GOLPH3L in cancer - Summary - The Human Protein Atlas

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GOLPH3L

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	GOLPH3L
Gene description	Golgi phosphoprotein 3-like
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Cell line enriched (U-698)
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA028558
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA028558

GENE INFORMATION
Gene name	GOLPH3L (HGNC Symbol)
Synonyms	GPP34R
Description	Golgi phosphoprotein 3-like (HGNC Symbol)
Entrez gene summary	The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is localized at the Golgi stack and may have a regulatory role in Golgi trafficking. [provided by RefSeq, Jul 2008]
Chromosome	1
Cytoband	q21.3
Chromosome location (bp)	150646225 - 150697144
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000143457 (version 83.38)
Entrez gene	55204
UniProt	Q9H4A5 (UniProt - Evidence at protein level)
neXtProt	NX_Q9H4A5
Antibodypedia	GOLPH3L antibodies

PROTEIN BROWSER

GOLPH3L-001	GOLPH3L-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GOLPH3L-001 ENSP00000271732 ENST00000271732	Q9H4A5 [Direct mapping] Golgi phosphoprotein 3-like Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0005515 [protein binding] GO:0007030 [Golgi organization] GO:0032580 [Golgi cisterna membrane] GO:0032588 [trans-Golgi network membrane] GO:0050714 [positive regulation of protein secretion] GO:0070273 [phosphatidylinositol-4-phosphate binding] Show all	285 aa 32.8 kDa	No	0
GOLPH3L-002 ENSP00000410476 ENST00000427665	Q5T5I6 [Direct mapping] Golgi phosphoprotein 3-like Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		269 aa 31.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.