Expression of NUP210L in cancer - Summary - The Human Protein Atlas

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NUP210L

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TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	NUP210L
Gene description	Nucleoporin 210kDa-like
Protein class	Cancer-related genes Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Cell line enriched (MCF7)
HPA (normal tissue):	Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Selective cytoplasmic expression in seminiferous ducts.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Presumed off target binding observed and disregarded.
Reliability score	Supported based on 2 antibodies. HPA064245 , HPA066707
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA064245	HPA066707

GENE INFORMATION
Gene name	NUP210L
Synonyms
Description	Nucleoporin 210kDa-like (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	q21.3
Chromosome location (bp)	153992685 - 154155116
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000143552 (version 83.38)
Entrez gene	91181
UniProt	Q5VU65 (UniProt - Evidence at transcript level)
neXtProt	NX_Q5VU65
Antibodypedia	NUP210L antibodies

PROTEIN BROWSER

NUP210L-001	NUP210L-002	NUP210L-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
NUP210L-001 ENSP00000357547 ENST00000368559	Q5VU65 [Direct mapping] Nuclear pore membrane glycoprotein 210-like Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Cancer-related genes Mutated cancer genes Protein evidence (Kim et al 2014) Show all	GO:0007286 [spermatid development] GO:0016021 [integral component of membrane] GO:0060009 [Sertoli cell development] Show all	1888 aa 210.6 kDa	Yes	2
NUP210L-002 ENSP00000357541 ENST00000368553	X6R6V8 [Direct mapping] Nuclear pore membrane glycoprotein 210-like Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Cancer-related genes Mutated cancer genes Show all	GO:0016021 [integral component of membrane] Show all	669 aa 73.9 kDa	No	1
NUP210L-201 ENSP00000271854 ENST00000271854	Q5VU65 [Direct mapping] Nuclear pore membrane glycoprotein 210-like Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Cancer-related genes Mutated cancer genes Protein evidence (Kim et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	1736 aa 194 kDa	Yes	1

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.