Tissue expression of RIT1 - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

RIT1

TISSUE

CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	RIT1
Gene description	Ras-like without CAAX 1
Protein class	Cancer-related genes Disease related genes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in several tissues.

DATA RELIABILITY
Data reliability description	Pending external verification.
Reliability score	Approved based on 1 antibody. HPA053249
	SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	RIT1 (HGNC Symbol)
Synonyms	MGC125864, MGC125865, RIBB, RIT, ROC1
Description	Ras-like without CAAX 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of a subfamily of Ras-related GTPases. The encoded protein is involved in regulating p38 MAPK-dependent signaling cascades related to cellular stress. This protein also cooperates with nerve growth factor to promote neuronal development and regeneration. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
Chromosome	1
Cytoband	q22
Chromosome location (bp)	155897808 - 155911404
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000143622 (version 83.38)
Entrez gene	6016
UniProt	Q92963 (UniProt - Evidence at protein level)
neXtProt	NX_Q92963
Antibodypedia	RIT1 antibodies

PROTEIN BROWSER

RIT1-001	RIT1-002	RIT1-005	RIT1-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RIT1-001 ENSP00000357306 ENST00000368323	Q92963 [Direct mapping] GTP-binding protein Rit1 Show all	Predicted intracellular proteins Cancer-related genes Mutated cancer genes Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003924 [GTPase activity] GO:0005515 [protein binding] GO:0005516 [calmodulin binding] GO:0005525 [GTP binding] GO:0005622 [intracellular] GO:0005886 [plasma membrane] GO:0006886 [intracellular protein transport] GO:0006913 [nucleocytoplasmic transport] GO:0007165 [signal transduction] GO:0007264 [small GTPase mediated signal transduction] GO:0007265 [Ras protein signal transduction] GO:0015031 [protein transport] GO:0016020 [membrane] GO:0048011 [neurotrophin TRK receptor signaling pathway] Show all	219 aa 25.1 kDa	No	0
RIT1-002 ENSP00000357305 ENST00000368322	Q92963 [Direct mapping] GTP-binding protein Rit1 Show all	Predicted intracellular proteins Cancer-related genes Mutated cancer genes Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003924 [GTPase activity] GO:0005515 [protein binding] GO:0005516 [calmodulin binding] GO:0005525 [GTP binding] GO:0005622 [intracellular] GO:0005886 [plasma membrane] GO:0006886 [intracellular protein transport] GO:0006913 [nucleocytoplasmic transport] GO:0007165 [signal transduction] GO:0007264 [small GTPase mediated signal transduction] GO:0007265 [Ras protein signal transduction] GO:0015031 [protein transport] GO:0016020 [membrane] GO:0048011 [neurotrophin TRK receptor signaling pathway] Show all	236 aa 27.1 kDa	No	0
RIT1-005 ENSP00000441950 ENST00000539040	Q92963 [Direct mapping] GTP-binding protein Rit1 Show all	Predicted intracellular proteins Cancer-related genes Mutated cancer genes Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005516 [calmodulin binding] GO:0005525 [GTP binding] GO:0005622 [intracellular] GO:0005886 [plasma membrane] GO:0007165 [signal transduction] GO:0007264 [small GTPase mediated signal transduction] GO:0007265 [Ras protein signal transduction] GO:0015031 [protein transport] GO:0016020 [membrane] GO:0048011 [neurotrophin TRK receptor signaling pathway] Show all	183 aa 21.6 kDa	No	0
RIT1-006 ENSP00000476612 ENST00000609492	V9GYC3 [Direct mapping] GTP-binding protein Rit1 Show all	Predicted intracellular proteins Cancer-related genes Mutated cancer genes Protein evidence (Ezkurdia et al 2014) Show all	GO:0005525 [GTP binding] GO:0005622 [intracellular] GO:0007165 [signal transduction] GO:0007264 [small GTPase mediated signal transduction] GO:0015031 [protein transport] GO:0016020 [membrane] Show all	151 aa 17 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.