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The product of this gene belongs to the phosphotyrosine protein phosphatase family of proteins. It functions as an acid phosphatase and a protein tyrosine phosphatase by hydrolyzing protein tyrosine phosphate to protein tyrosine and orthophosphate. This enzyme also hydrolyzes orthophosphoric monoesters to alcohol and orthophosphate. This gene is genetically polymorphic, and three common alleles segregating at the corresponding locus give rise to six phenotypes. Each allele appears to encode at least two electrophoretically different isozymes, Bf and Bs, which are produced in allele-specific ratios. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Aug 2008]
P24666 [Direct mapping] Low molecular weight phosphotyrosine protein phosphatase
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Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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GO:0003993 [acid phosphatase activity] GO:0004726 [non-membrane spanning protein tyrosine phosphatase activity] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0009898 [cytoplasmic side of plasma membrane] GO:0035335 [peptidyl-tyrosine dephosphorylation] GO:0070062 [extracellular exosome]
P24666 [Direct mapping] Low molecular weight phosphotyrosine protein phosphatase
Show all
Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
P24666 [Direct mapping] Low molecular weight phosphotyrosine protein phosphatase
Show all
Enzymes ENZYME proteins Hydrolases Phobius predicted membrane proteins TMHMM predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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GO:0003993 [acid phosphatase activity] GO:0004726 [non-membrane spanning protein tyrosine phosphatase activity] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0009898 [cytoplasmic side of plasma membrane] GO:0035335 [peptidyl-tyrosine dephosphorylation] GO:0070062 [extracellular exosome]
