Cell atlas - SLC26A1 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

SLC26A1

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Microtubules

Human cell
	Microtubules

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	SLC26A1
Gene description	Solute carrier family 26 (anion exchanger), member 1
Protein class	Plasma proteins Predicted membrane proteins Transporters
Predicted localization	Membrane
Number of transcripts	4
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the microtubules.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Microtubules (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA041654
	SHOW MORE

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the microtubules.

Main location

Microtubules (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA041654	Hep G2	Microtubules
	HPA041654	U-2 OS	Microtubules
	HPA041654	U-251 MG	Microtubules

GENE INFORMATION
Gene name	SLC26A1 (HGNC Symbol)
Synonyms	EDM4, SAT-1
Description	Solute carrier family 26 (anion exchanger), member 1 (HGNC Symbol)
Entrez gene summary	This gene is a member of a family of sulfate/anion transporter genes. Family members are well conserved in their genomic (number and size of exons) and protein (aa length among species) structures, but have markedly different tissue expression patterns. This gene is primarily expressed in the liver, pancreas, and brain. Three splice variants that encode different isoforms have been identified. [provided by RefSeq, Jul 2008]
Chromosome	4
Cytoband	p16.3
Chromosome location (bp)	979073 - 993440
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000145217 (version 83.38)
Entrez gene	10861
UniProt	Q9H2B4 (UniProt - Evidence at protein level)
neXtProt	NX_Q9H2B4
Antibodypedia	SLC26A1 antibodies

PROTEIN BROWSER

SLC26A1-001	SLC26A1-002	SLC26A1-003	SLC26A1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC26A1-001 ENSP00000354721 ENST00000361661	Q9H2B4 [Direct mapping] Sulfate anion transporter 1 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005254 [chloride channel activity] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0005975 [carbohydrate metabolic process] GO:0006805 [xenobiotic metabolic process] GO:0006811 [ion transport] GO:0006821 [chloride transport] GO:0008271 [secondary active sulfate transmembrane transporter activity] GO:0008272 [sulfate transport] GO:0015106 [bicarbonate transmembrane transporter activity] GO:0015108 [chloride transmembrane transporter activity] GO:0015116 [sulfate transmembrane transporter activity] GO:0015301 [anion:anion antiporter activity] GO:0015701 [bicarbonate transport] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0019531 [oxalate transmembrane transporter activity] GO:0019532 [oxalate transport] GO:0030203 [glycosaminoglycan metabolic process] GO:0042391 [regulation of membrane potential] GO:0044281 [small molecule metabolic process] GO:0050427 [3'-phosphoadenosine 5'-phosphosulfate metabolic process] GO:0050428 [3'-phosphoadenosine 5'-phosphosulfate biosynthetic process] GO:0051453 [regulation of intracellular pH] GO:0055085 [transmembrane transport] GO:1902358 [sulfate transmembrane transport] GO:1902476 [chloride transmembrane transport] Show all	701 aa 75 kDa	No	>9
SLC26A1-002 ENSP00000381528 ENST00000398516	Q9H2B4 [Direct mapping] Sulfate anion transporter 1 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005254 [chloride channel activity] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0005975 [carbohydrate metabolic process] GO:0006805 [xenobiotic metabolic process] GO:0006811 [ion transport] GO:0006821 [chloride transport] GO:0008271 [secondary active sulfate transmembrane transporter activity] GO:0008272 [sulfate transport] GO:0015106 [bicarbonate transmembrane transporter activity] GO:0015108 [chloride transmembrane transporter activity] GO:0015116 [sulfate transmembrane transporter activity] GO:0015301 [anion:anion antiporter activity] GO:0015701 [bicarbonate transport] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0019531 [oxalate transmembrane transporter activity] GO:0019532 [oxalate transport] GO:0030203 [glycosaminoglycan metabolic process] GO:0042391 [regulation of membrane potential] GO:0044281 [small molecule metabolic process] GO:0050427 [3'-phosphoadenosine 5'-phosphosulfate metabolic process] GO:0050428 [3'-phosphoadenosine 5'-phosphosulfate biosynthetic process] GO:0051453 [regulation of intracellular pH] GO:0055085 [transmembrane transport] GO:1902358 [sulfate transmembrane transport] GO:1902476 [chloride transmembrane transport] Show all	701 aa 75 kDa	No	>9
SLC26A1-003 ENSP00000381532 ENST00000398520	Q9H2B4 [Direct mapping] Sulfate anion transporter 1 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005254 [chloride channel activity] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0005975 [carbohydrate metabolic process] GO:0006805 [xenobiotic metabolic process] GO:0006811 [ion transport] GO:0006821 [chloride transport] GO:0008271 [secondary active sulfate transmembrane transporter activity] GO:0008272 [sulfate transport] GO:0015106 [bicarbonate transmembrane transporter activity] GO:0015108 [chloride transmembrane transporter activity] GO:0015116 [sulfate transmembrane transporter activity] GO:0015301 [anion:anion antiporter activity] GO:0015701 [bicarbonate transport] GO:0016021 [integral component of membrane] GO:0019531 [oxalate transmembrane transporter activity] GO:0019532 [oxalate transport] GO:0030203 [glycosaminoglycan metabolic process] GO:0042391 [regulation of membrane potential] GO:0044281 [small molecule metabolic process] GO:0050427 [3'-phosphoadenosine 5'-phosphosulfate metabolic process] GO:0050428 [3'-phosphoadenosine 5'-phosphosulfate biosynthetic process] GO:0051453 [regulation of intracellular pH] GO:0055085 [transmembrane transport] GO:1902358 [sulfate transmembrane transport] GO:1902476 [chloride transmembrane transport] Show all	224 aa 25 kDa	No	3
SLC26A1-201 ENSP00000483506 ENST00000622731	Q9H2B4 [Direct mapping] Sulfate anion transporter 1 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005254 [chloride channel activity] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0005975 [carbohydrate metabolic process] GO:0006805 [xenobiotic metabolic process] GO:0006811 [ion transport] GO:0006821 [chloride transport] GO:0008271 [secondary active sulfate transmembrane transporter activity] GO:0008272 [sulfate transport] GO:0015106 [bicarbonate transmembrane transporter activity] GO:0015108 [chloride transmembrane transporter activity] GO:0015116 [sulfate transmembrane transporter activity] GO:0015301 [anion:anion antiporter activity] GO:0015701 [bicarbonate transport] GO:0016021 [integral component of membrane] GO:0019531 [oxalate transmembrane transporter activity] GO:0019532 [oxalate transport] GO:0030203 [glycosaminoglycan metabolic process] GO:0042391 [regulation of membrane potential] GO:0044281 [small molecule metabolic process] GO:0050427 [3'-phosphoadenosine 5'-phosphosulfate metabolic process] GO:0050428 [3'-phosphoadenosine 5'-phosphosulfate biosynthetic process] GO:0051453 [regulation of intracellular pH] GO:0055085 [transmembrane transport] GO:1902358 [sulfate transmembrane transport] GO:1902476 [chloride transmembrane transport] Show all	224 aa 25 kDa	No	3

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.