Cell atlas - ANO7 - The Human Protein Atlas

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ANO7

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	ANO7
Gene description	Anoctamin 7
Protein class	Predicted membrane proteins Predicted secreted proteins
Predicted localization	Membrane,Secreted
Number of transcripts	4
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (BEWO, Hep G2)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (BEWO, Hep G2) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	ANO7 (HGNC Symbol)
Synonyms	IPCA-5, NGEP, PCANAP5, PCANAP5L, TMEM16G
Description	Anoctamin 7 (HGNC Symbol)
Entrez gene summary	This prostate-specific gene encodes a cytoplasmic protein, as well as a polytopic membrane protein which may serve as a target in prostate cancer diagnosis and immunotherapy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2011]
Chromosome	2
Cytoband	q37.3
Chromosome location (bp)	241188509 - 241225377
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000146205 (version 83.38)
Entrez gene	50636
UniProt	Q6IWH7 (UniProt - Evidence at protein level)
neXtProt	NX_Q6IWH7
Antibodypedia	ANO7 antibodies

PROTEIN BROWSER

ANO7-001	ANO7-002	ANO7-008	ANO7-010

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ANO7-001 ENSP00000274979 ENST00000274979	Q6IWH7 [Direct mapping] Anoctamin-7 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 9TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005229 [intracellular calcium activated chloride channel activity] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0005783 [endoplasmic reticulum] GO:0005829 [cytosol] GO:0005886 [plasma membrane] GO:0006821 [chloride transport] GO:0006869 [lipid transport] GO:0016021 [integral component of membrane] GO:0017128 [phospholipid scramblase activity] GO:0030054 [cell junction] GO:0034220 [ion transmembrane transport] GO:0055085 [transmembrane transport] GO:0061589 [calcium activated phosphatidylserine scrambling] GO:0061590 [calcium activated phosphatidylcholine scrambling] GO:0061591 [calcium activated galactosylceramide scrambling] GO:1902476 [chloride transmembrane transport] Show all	933 aa 105.5 kDa	Yes	9
ANO7-002 ENSP00000383985 ENST00000402530	Q6IWH7 [Direct mapping] Anoctamin-7 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005229 [intracellular calcium activated chloride channel activity] GO:0005622 [intracellular] GO:0005783 [endoplasmic reticulum] GO:0005829 [cytosol] GO:0005886 [plasma membrane] GO:0006821 [chloride transport] GO:0006869 [lipid transport] GO:0016021 [integral component of membrane] GO:0030054 [cell junction] GO:0034220 [ion transmembrane transport] GO:0055085 [transmembrane transport] Show all	179 aa 19.6 kDa	Yes	0
ANO7-008 ENSP00000403625 ENST00000451047	H7C220 [Direct mapping] Anoctamin Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] GO:0061588 [calcium activated phospholipid scrambling] Show all	186 aa 20.9 kDa	No	3
ANO7-010 ENSP00000385418 ENST00000402430	Q6IWH7 [Direct mapping] Anoctamin-7 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 9TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005229 [intracellular calcium activated chloride channel activity] GO:0005622 [intracellular] GO:0005783 [endoplasmic reticulum] GO:0005829 [cytosol] GO:0005886 [plasma membrane] GO:0006821 [chloride transport] GO:0006869 [lipid transport] GO:0016021 [integral component of membrane] GO:0030054 [cell junction] GO:0034220 [ion transmembrane transport] GO:0055085 [transmembrane transport] Show all	883 aa 99.8 kDa	Yes	9

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.