Cell atlas - ZMYM4 - The Human Protein Atlas

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ZMYM4

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS MOUSE CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Nucleoplasm

Human cell
	Cytosol
	Nucleoplasm

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GENERAL INFORMATION
Gene name	ZMYM4
Gene description	Zinc finger, MYM-type 4
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the nucleoplasm. In addition localized to the cytosol.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (supported)
Additional location	In addition localized to the Cytosol (supported)
Single-cell variation	Single-cell variation in protein expression observed.
Mouse	Localized to the Nucleoplasm in mouse cells.

DATA RELIABILITY
Reliability score	Supported based on 2 antibodies. HPA051301 , HPA054802
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ASSAYS

RNA expression

Human cells

Mouse cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the nucleoplasm. In addition localized to the cytosol.

Main location

Nucleoplasm (supported)

Additional location

Cytosol (supported)


	Toggle channels	Low High G1 S G2 M N/A

Antibody	Cell line	Location	Single-cell variation
HPA051301	A-431	Nucleoplasm
HPA051301	A-431	Cytosol
HPA051301	HEK 293	Nucleoplasm
HPA051301	HEK 293	Cytosol
HPA051301	U-2 OS	Nucleoplasm
HPA051301	U-2 OS	Cytosol
HPA054802	A-431	Nucleoplasm
HPA054802	A-431	Cytosol
HPA054802	HEK 293	Nucleoplasm
HPA054802	U-2 OS	Nucleus
		Nucleoli	Intensity
		Cytosol

MOUSE CELLS

Main location

Nucleoplasm

Mouse gene

ENSMUSG00000042446 (version 83)


	Toggle channels	Low High G1 S G2 M N/A

Antibody	Cell line	Location
HPA051301	NIH 3T3	Nucleoplasm
HPA051301	NIH 3T3	Cytosol
HPA054802	NIH 3T3	Nucleoplasm

GENE INFORMATION
Gene name	ZMYM4 (HGNC Symbol)
Synonyms	KIAA0425, MYM, ZNF198L3, ZNF262
Description	Zinc finger, MYM-type 4 (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	p34.3
Chromosome location (bp)	35268967 - 35422058
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000146463 (version 83.38)
Entrez gene	9202
UniProt	Q5VZL5 (UniProt - Evidence at protein level)
neXtProt	NX_Q5VZL5
Antibodypedia	ZMYM4 antibodies

PROTEIN BROWSER

ZMYM4-001	ZMYM4-002	ZMYM4-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZMYM4-001 ENSP00000322915 ENST00000314607	Q5VZL5 [Direct mapping] Zinc finger MYM-type protein 4 Show all	MEMSAT3 predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0007010 [cytoskeleton organization] GO:0007275 [multicellular organismal development] GO:0008270 [zinc ion binding] GO:0022604 [regulation of cell morphogenesis] Show all	1548 aa 172.8 kDa	No	0
ZMYM4-002 ENSP00000397524 ENST00000441447	A0A0A0MSN3 [Direct mapping] Zinc finger MYM-type protein 4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		98 aa 10.9 kDa	No	0
ZMYM4-003 ENSP00000400506 ENST00000457946	H7C1I7 [Direct mapping] Zinc finger MYM-type protein 4 Show all	MEMSAT3 predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008270 [zinc ion binding] Show all	1207 aa 134.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.