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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

Cancer

Prognosis

Category

Score

Score

Score

Antibodies

Column

 
 
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CDCA5
  • TISSUE

  • premium

    CELL

  • PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

CDCA5

Gene description

Cell division cycle associated 5

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

4
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Tissue enhanced (bone marrow, testis)
GTEx:Tissue enriched (testis)
FANTOM5:Tissue enhanced (appendix, testis)

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in several tissues, including nuclear expression in lymphoid and gastrointestinal tissue.

DATA RELIABILITY

Data reliability
description

Antibody staining mainly not consistent with RNA expression data. Presumed off target binding observed and disregarded.

Reliability score

Approved based on 1 antibody.
HPA023691
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (bone marrow, testis)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (appendix, testis)

GENE INFORMATION

Gene name

CDCA5

Synonyms

Description

Cell division cycle associated 5 (HGNC Symbol)

Entrez gene summary

Chromosome

11

Cytoband

q13.1

Chromosome location (bp)

65066300 - 65084164

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000146670 (version 83.38)

Entrez gene

113130

UniProt

Q96FF9 (UniProt - Evidence at protein level)

neXtProt

NX_Q96FF9

Antibodypedia

CDCA5 antibodies

PROTEIN BROWSER

CDCA5-001
CDCA5-005
CDCA5-007
CDCA5-009

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CDCA5-001
ENSP00000275517
ENST00000275517
Q96FF9 [Direct mapping]
Sororin
A0A024R5D6 [Target identity:100%; Query identity:100%]
Cell division cycle associated 5, isoform CRA_a
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000082 [G1/S transition of mitotic cell cycle]
GO:0000278 [mitotic cell cycle]
GO:0000775 [chromosome, centromeric region]
GO:0000785 [chromatin]
GO:0000790 [nuclear chromatin]
GO:0003682 [chromatin binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005694 [chromosome]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0006302 [double-strand break repair]
GO:0007064 [mitotic sister chromatid cohesion]
GO:0007067 [mitotic nuclear division]
GO:0007076 [mitotic chromosome condensation]
GO:0007080 [mitotic metaphase plate congression]
GO:0008278 [cohesin complex]
GO:0031536 [positive regulation of exit from mitosis]
GO:0051301 [cell division]
GO:0071922 [regulation of cohesin localization to chromatin]
GO:1901989 [positive regulation of cell cycle phase transition]
Show all
252 aa
27.6 kDa
No 0
CDCA5-005
ENSP00000385711
ENST00000404147
B5MBX0 [Direct mapping]
Sororin
Show all
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005654 [nucleoplasm]
GO:0005886 [plasma membrane]
Show all
307 aa
33.7 kDa
No 0
CDCA5-007
ENSP00000432183
ENST00000529290
H0YCR8 [Direct mapping]
Sororin
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
254 aa
28.2 kDa
No 0
CDCA5-009
ENSP00000432342
ENST00000525464
H0YCT9 [Direct mapping]
Sororin
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
224 aa
25.4 kDa
No 0

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