Fields »
ABOUT
HELP
BLOG
RIPPLY1

GENERAL INFORMATION

Gene name

 RIPPLY1

Gene description

 Ripply transcriptional repressor 1

Protein class

 Predicted secreted proteins

Predicted localization

 Secreted

Number of transcripts

 2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Group enriched (liver cancer, renal cancer, testis cancer)
HPA (cell line):Cell line enriched (RH-30)
HPA (normal tissue):Tissue enhanced (kidney, liver)

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY

Data reliability
description

 RNA-based expert annotation gave inconclusive results. Pending external verification.

Reliability score

 Uncertain based on 1 antibody.
HPA052284
SHOW MORE

PROGNOSTIC SUMMARY
Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Group enriched (liver cancer, renal cancer, testis cancer)

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA052284

GENE INFORMATION

Gene name

 RIPPLY1

Synonyms

Description

 Ripply transcriptional repressor 1 (HGNC Symbol)

Entrez gene summary

 This gene encodes a protein similar to a zebrafish protein which acts as a transcriptional repressor in and is required for somite segmentation in zebrafish embryos (PMID: 16326386). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

Chromosome

 X

Cytoband

 q22.3

Chromosome location (bp)

 106900063 - 106903335

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000147223 (version 83.38)

Entrez gene

 92129

UniProt

 Q0D2K3 (UniProt - Evidence at protein level)

neXtProt

 NX_Q0D2K3

Antibodypedia

 RIPPLY1 antibodies

PROTEIN BROWSER
RIPPLY1-001
RIPPLY1-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RIPPLY1-001
ENSP00000400539
ENST00000411805
Q0D2K3 [Direct mapping]
Protein ripply1
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0001757 [somite specification]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0009880 [embryonic pattern specification]
GO:0032525 [somite rostral/caudal axis specification]
GO:0045892 [negative regulation of transcription, DNA-templated]
Show all
 104 aa
11.2 kDa 		Yes 0
RIPPLY1-002
ENSP00000276173
ENST00000276173
Q0D2K3 [Direct mapping]
Protein ripply1
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0001757 [somite specification]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0007219 [Notch signaling pathway]
GO:0009880 [embryonic pattern specification]
GO:0010468 [regulation of gene expression]
GO:0032525 [somite rostral/caudal axis specification]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0060349 [bone morphogenesis]
Show all
 151 aa
16.4 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.