Tissue expression of RIPPLY1 - Summary - The Human Protein Atlas

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RIPPLY1

TISSUE

CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	RIPPLY1
Gene description	Ripply transcriptional repressor 1
Protein class	Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (kidney, liver)
GTEx:	Tissue enhanced (kidney, liver)
FANTOM5:	Not detected

Protein evidence

Evidence at protein level

Protein expression

Estimation of protein expression could not be performed. View primary data.

DATA RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA052284
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

N/A

Caudate

N/A

N/A

Cerebellum

N/A

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

N/A

Bronchus

N/A

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

N/A

Skin

N/A

Skin

N/A

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (kidney, liver)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (kidney, liver)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Not detected

GENE INFORMATION
Gene name	RIPPLY1
Synonyms
Description	Ripply transcriptional repressor 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein similar to a zebrafish protein which acts as a transcriptional repressor in and is required for somite segmentation in zebrafish embryos (PMID: 16326386). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Chromosome	X
Cytoband	q22.3
Chromosome location (bp)	106900063 - 106903335
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000147223 (version 83.38)
Entrez gene	92129
UniProt	Q0D2K3 (UniProt - Evidence at protein level)
neXtProt	NX_Q0D2K3
Antibodypedia	RIPPLY1 antibodies

PROTEIN BROWSER

RIPPLY1-001	RIPPLY1-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RIPPLY1-001 ENSP00000400539 ENST00000411805	Q0D2K3 [Direct mapping] Protein ripply1 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0001757 [somite specification] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0009880 [embryonic pattern specification] GO:0032525 [somite rostral/caudal axis specification] GO:0045892 [negative regulation of transcription, DNA-templated] Show all	104 aa 11.2 kDa	Yes	0
RIPPLY1-002 ENSP00000276173 ENST00000276173	Q0D2K3 [Direct mapping] Protein ripply1 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0001757 [somite specification] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0007219 [Notch signaling pathway] GO:0009880 [embryonic pattern specification] GO:0010468 [regulation of gene expression] GO:0032525 [somite rostral/caudal axis specification] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0060349 [bone morphogenesis] Show all	151 aa 16.4 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.