Fields »
ABOUT
HELP
BLOG
FATE1

GENERAL INFORMATION

Gene name

 FATE1

Gene description

 Fetal and adult testis expressed 1

Protein class

 Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

 Intracellular,Membrane

Number of transcripts

 2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enriched (testis)
GTEx:Tissue enriched (testis)
FANTOM5:Tissue enriched (testis)

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression of cells in seminiferous ducts in testis.

DATA RELIABILITY

Data reliability
description

 Antibody staining consistent with RNA expression data.

Reliability score

 Supported based on 1 antibody.
HPA034604
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)

GENE INFORMATION

Gene name

 FATE1 (HGNC Symbol)

Synonyms

 CT43, FATE

Description

 Fetal and adult testis expressed 1 (HGNC Symbol)

Entrez gene summary

 This gene encodes a cancer-testis antigen that is highly expressed in hepatocellular carcinomas and other tumors and weakly expressed in normal tissues except testis. The protein is strongly expressed in spermatogonia, primary spermatocytes, and Sertoli cells in seminiferous tubules. This protein may have a role in the control of early testicular differentiation and cell proliferation. [provided by RefSeq, Jan 2010]

Chromosome

 X

Cytoband

 q28

Chromosome location (bp)

 151716035 - 151723194

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000147378 (version 83.38)

Entrez gene

 89885

UniProt

 Q969F0 (UniProt - Evidence at protein level)

neXtProt

 NX_Q969F0

Antibodypedia

 FATE1 antibodies

PROTEIN BROWSER
FATE1-001
FATE1-003

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
FATE1-001
ENSP00000359375
ENST00000370350
Q969F0 [Direct mapping]
Fetal and adult testis-expressed transcript protein
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005783 [endoplasmic reticulum]
GO:0016021 [integral component of membrane]
Show all
 183 aa
20.7 kDa 		No 1
FATE1-003
ENSP00000400493
ENST00000417321
H7C1I5 [Direct mapping]
Fetal and adult testis-expressed transcript protein
Show all
Predicted intracellular proteins
Show all
 80 aa
8.9 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.