Cell atlas - BIN3 - The Human Protein Atlas

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BIN3

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	BIN3
Gene description	Bridging integrator 3
Protein class	Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	BIN3
Synonyms
Description	Bridging integrator 3 (HGNC Symbol)
Entrez gene summary	The product of this gene is a member of the BAR domain protein family. The encoded protein is comprised solely of a BAR domain which is predicted to form coiled-coil structures and proposed to mediate dimerization, sense and induce membrane curvature, and bind small GTPases. BAR domain proteins have been implicated in endocytosis, intracellular transport, and a diverse set of other processes. [provided by RefSeq, Jul 2008]
Chromosome	8
Cytoband	p21.3
Chromosome location (bp)	22620418 - 22669148
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000147439 (version 83.38)
Entrez gene	55909
UniProt	Q9NQY0 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NQY0
Antibodypedia	BIN3 antibodies

PROTEIN BROWSER

BIN3-001	BIN3-002	BIN3-003	BIN3-007	BIN3-011

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
BIN3-001 ENSP00000276416 ENST00000276416	Q9NQY0 [Direct mapping] Bridging integrator 3 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000910 [cytokinesis] GO:0000917 [barrier septum assembly] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005884 [actin filament] GO:0007015 [actin filament organization] GO:0008093 [cytoskeletal adaptor activity] GO:0008104 [protein localization] GO:0009826 [unidimensional cell growth] GO:0010591 [regulation of lamellipodium assembly] GO:0014839 [myoblast migration involved in skeletal muscle regeneration] GO:0043403 [skeletal muscle tissue regeneration] GO:0048741 [skeletal muscle fiber development] Show all	253 aa 29.7 kDa	No	0
BIN3-002 ENSP00000430423 ENST00000519513	Q9NQY0 [Direct mapping] Bridging integrator 3 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000910 [cytokinesis] GO:0000917 [barrier septum assembly] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0007015 [actin filament organization] GO:0008093 [cytoskeletal adaptor activity] GO:0008104 [protein localization] GO:0009826 [unidimensional cell growth] Show all	199 aa 23.2 kDa	No	0
BIN3-003 ENSP00000382859 ENST00000399977	H7BYV6 [Direct mapping] Bridging integrator 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] Show all	205 aa 23.9 kDa	No	0
BIN3-007 ENSP00000428768 ENST00000522268	E5RGB5 [Direct mapping] Bridging integrator 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		27 aa 3.1 kDa	No	0
BIN3-011 ENSP00000429660 ENST00000520292	E5RHU4 [Direct mapping] Bridging integrator 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		149 aa 17.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.