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Term
Gene name

Class

Subclass

Chromosome

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In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

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Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

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Detectable

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PLPP5
  • TISSUE

  • CELL

  • PATHOLOGY

TISSUE ATLAS

GENE/PROTEIN

Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

PLPP5

Gene description

Phospholipid phosphatase 5

Protein class

Enzymes
Predicted membrane proteins

Predicted localization

Membrane

Number of transcripts

7
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY

Reliability score

Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
N/A
Cerebral cortex
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Thyroid gland
N/A
Parathyroid gland
N/A
Adrenal gland
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Bone marrow
N/A
Lymph node
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Heart muscle
N/A
Skeletal muscle
N/A
Smooth muscle
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Gallbladder
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Salivary gland
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Small intestine
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
Prostate
N/A
Seminal vesicle
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
Endometrium
N/A
Fallopian tube
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Adipose tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A

PROTEIN EXPRESSION OVERVIEW

Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
Cerebral cortexThyroid glandParathyroid glandAdrenal glandAppendixBone marrowLymph nodeTonsilSpleenHeart muscleSkeletal muscleSmooth muscleLungLiverGallbladderPancreasSalivary glandEsophagusStomachDuodenumSmall intestineColonRectumKidneyUrinary bladderTestisEpididymisProstateSeminal vesicleBreastCervix, uterineEndometriumFallopian tubeOvaryPlacentaAdipose tissueSkin020406080100120140TPM
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
HypothalamusPituitary glandCerebral cortexHippocampusCaudateCerebellumThyroid glandAdrenal glandSpleenHeart muscleSkeletal muscleLungLiverPancreasSalivary glandEsophagusStomachSmall intestineColonKidneyUrinary bladderTestisProstateBreastVaginaCervix, uterineEndometriumFallopian tubeOvaryAdipose tissueSkin010203040RPKM
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
Pituitary glandBrainHippocampusCaudateCerebellumThyroid glandAppendixLymph nodeTonsilSpleenHeart muscleSkeletal muscleSmooth muscleLungLiverGallbladderPancreasSalivary glandEsophagusSmall intestineColonKidneyUrinary bladderTestisEpididymisProstateSeminal vesicleBreastVaginaCervix, uterineEndometriumOvaryPlacentaAdipose tissueRetina050100150200Tags Per Million

GENE INFORMATION

Gene name

PLPP5 (HGNC Symbol)

Synonyms

DPPL1, HTPAP, PPAPDC1B

Description

Phospholipid phosphatase 5 (HGNC Symbol)

Entrez gene summary

Chromosome

8

Cytoband

p11.23

Chromosome location (bp)

38263130 - 38269243

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000147535 (version 83.38)

Entrez gene

84513

UniProt

Q8NEB5 (UniProt - Evidence at protein level)

neXtProt

NX_Q8NEB5

Antibodypedia

PLPP5 antibodies

PROTEIN BROWSER

PLPP5-001
PLPP5-002
PLPP5-003
PLPP5-005
PLPP5-006
PLPP5-007
PLPP5-015

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PLPP5-001
ENSP00000392553
ENST00000424479
Q8NEB5 [Direct mapping]
Phosphatidate phosphatase PPAPDC1B
Show all
Enzymes
   ENZYME proteins
   Hydrolases
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   6TM proteins predicted by MDM
Show all
GO:0005737 [cytoplasm]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006644 [phospholipid metabolic process]
GO:0007165 [signal transduction]
GO:0008195 [phosphatidate phosphatase activity]
GO:0046839 [phospholipid dephosphorylation]
Show all
264 aa
29.5 kDa
No 6
PLPP5-002
ENSP00000390622
ENST00000422581
Q8NEB5 [Direct mapping]
Phosphatidate phosphatase PPAPDC1B
Show all
Enzymes
   ENZYME proteins
   Hydrolases
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   5TM proteins predicted by MDM
Show all
GO:0005737 [cytoplasm]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006644 [phospholipid metabolic process]
GO:0007165 [signal transduction]
GO:0008195 [phosphatidate phosphatase activity]
GO:0046839 [phospholipid dephosphorylation]
Show all
216 aa
24.1 kDa
No 5
PLPP5-003
ENSP00000414522
ENST00000419686
Q8NEB5 [Direct mapping]
Phosphatidate phosphatase PPAPDC1B
Show all
Enzymes
   ENZYME proteins
   Hydrolases
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   3TM proteins predicted by MDM
Show all
GO:0005737 [cytoplasm]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006644 [phospholipid metabolic process]
GO:0007165 [signal transduction]
GO:0008195 [phosphatidate phosphatase activity]
GO:0046839 [phospholipid dephosphorylation]
Show all
176 aa
19.7 kDa
No 3
PLPP5-005
ENSP00000434916
ENST00000529359
Q8NEB5 [Direct mapping]
Phosphatidate phosphatase PPAPDC1B
Show all
Enzymes
   ENZYME proteins
   Hydrolases
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   5TM proteins predicted by MDM
Show all
GO:0005737 [cytoplasm]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006644 [phospholipid metabolic process]
GO:0007165 [signal transduction]
GO:0008195 [phosphatidate phosphatase activity]
GO:0046839 [phospholipid dephosphorylation]
Show all
223 aa
25.2 kDa
No 5
PLPP5-006
ENSP00000431771
ENST00000534339
H0YCK0 [Direct mapping]
Phosphatidate phosphatase PPAPDC1B
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   5TM proteins predicted by MDM
Show all
GO:0008195 [phosphatidate phosphatase activity]
GO:0016021 [integral component of membrane]
GO:0046839 [phospholipid dephosphorylation]
Show all
244 aa
27.5 kDa
No 5
PLPP5-007
ENSP00000432122
ENST00000524616
H0YCQ3 [Direct mapping]
Phosphatidate phosphatase PPAPDC1B
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   5TM proteins predicted by MDM
Show all
GO:0008195 [phosphatidate phosphatase activity]
GO:0016021 [integral component of membrane]
GO:0046839 [phospholipid dephosphorylation]
Show all
245 aa
27.4 kDa
No 5
PLPP5-015
ENSP00000437248
ENST00000531823
E9PNB1 [Direct mapping]
Phosphatidate phosphatase PPAPDC1B
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   3TM proteins predicted by MDM
Show all
GO:0008195 [phosphatidate phosphatase activity]
GO:0016021 [integral component of membrane]
GO:0046839 [phospholipid dephosphorylation]
Show all
132 aa
14.8 kDa
No 3

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  • ORGANIZATION
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The Human Protein Atlas

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  • LICENCE & CITATION
  • HELP & FAQ
The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.