Cell atlas - EBAG9 - The Human Protein Atlas

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EBAG9

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Golgi apparatus

Human cell
	Golgi Apparatus

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GENERAL INFORMATION
Gene name	EBAG9
Gene description	Estrogen receptor binding site associated, antigen, 9
Protein class	Cancer-related genes Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	8
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the Golgi apparatus.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Golgi apparatus (validated)

DATA RELIABILITY
Reliability score	Validated based on 3 antibodies. CAB072810 , CAB072811 , CAB072812
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ASSAYS

RNA expression

Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the Golgi apparatus.

Main location

Golgi apparatus (validated)


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Antibody	Cell line	Location
CAB072810	HeLa	Golgi apparatus
CAB072810	MCF7	Golgi apparatus
CAB072810	U-2 OS	Golgi apparatus
CAB072811	HeLa	Golgi apparatus
CAB072811	MCF7	Golgi apparatus
CAB072811	U-2 OS	Golgi apparatus
CAB072812	HeLa	Golgi apparatus
CAB072812	MCF7	Golgi apparatus
CAB072812	U-2 OS	Golgi apparatus

GENE INFORMATION
Gene name	EBAG9 (HGNC Symbol)
Synonyms	EB9, RCAS1
Description	Estrogen receptor binding site associated, antigen, 9 (HGNC Symbol)
Entrez gene summary	This gene was identified as an estrogen-responsive gene. Regulation of transcription by estrogen is mediated by estrogen receptor, which binds to the estrogen-responsive element found in the 5'-flanking region of this gene. The encoded protein is a tumor-associated antigen that is expressed at high frequency in a variety of cancers. Alternate splicing results in multiple transcript variants. A pseudogene of this gene has been defined on chromosome 10. [provided by RefSeq, Jul 2013]
Chromosome	8
Cytoband	q23.2
Chromosome location (bp)	109539711 - 109565996
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000147654 (version 83.38)
Entrez gene	9166
UniProt	O00559 (UniProt - Evidence at protein level)
neXtProt	NX_O00559
Antibodypedia	EBAG9 antibodies

PROTEIN BROWSER

EBAG9-001	EBAG9-002	EBAG9-004	EBAG9-005	EBAG9-006	EBAG9-008	EBAG9-201	EBAG9-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
EBAG9-001 ENSP00000337675 ENST00000337573	O00559 [Direct mapping] Receptor-binding cancer antigen expressed on SiSo cells A0A024R9E0 [Target identity:100%; Query identity:100%] Estrogen receptor binding site associated, antigen, 9, isoform CRA_a Show all	SPOCTOPUS predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins Cancer-related genes Candidate cancer biomarkers Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0001558 [regulation of cell growth] GO:0005515 [protein binding] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005925 [focal adhesion] GO:0006915 [apoptotic process] GO:0016021 [integral component of membrane] GO:0016505 [peptidase activator activity involved in apoptotic process] GO:0030141 [secretory granule] Show all	213 aa 24.4 kDa	Yes	0
EBAG9-002 ENSP00000379131 ENST00000395785	O00559 [Direct mapping] Receptor-binding cancer antigen expressed on SiSo cells A0A024R9E0 [Target identity:100%; Query identity:100%] Estrogen receptor binding site associated, antigen, 9, isoform CRA_a Show all	SPOCTOPUS predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins Cancer-related genes Candidate cancer biomarkers Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0001558 [regulation of cell growth] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005925 [focal adhesion] GO:0006915 [apoptotic process] GO:0016021 [integral component of membrane] GO:0016505 [peptidase activator activity involved in apoptotic process] Show all	213 aa 24.4 kDa	Yes	0
EBAG9-004 ENSP00000435687 ENST00000529931	E9PJ40 [Direct mapping] Receptor-binding cancer antigen-expressed on SiSo cells Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		41 aa 4.5 kDa	No	0
EBAG9-005 ENSP00000434878 ENST00000530629	E9PN10 [Direct mapping] Receptor-binding cancer antigen-expressed on SiSo cells Show all	SPOCTOPUS predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005925 [focal adhesion] Show all	197 aa 22.5 kDa	Yes	0
EBAG9-006 ENSP00000435689 ENST00000534318	E9PJ38 [Direct mapping] Receptor-binding cancer antigen-expressed on SiSo cells Show all	SPOCTOPUS predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all		78 aa 8.7 kDa	Yes	0
EBAG9-008 ENSP00000432082 ENST00000531677	O00559 [Direct mapping] Receptor-binding cancer antigen expressed on SiSo cells Show all	SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins Cancer-related genes Candidate cancer biomarkers Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0001558 [regulation of cell growth] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005925 [focal adhesion] GO:0006915 [apoptotic process] GO:0016021 [integral component of membrane] GO:0016505 [peptidase activator activity involved in apoptotic process] Show all	258 aa 29.5 kDa	Yes	0
EBAG9-201 ENSP00000477734 ENST00000614147	O00559 [Direct mapping] Receptor-binding cancer antigen expressed on SiSo cells Show all	SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins Cancer-related genes Candidate cancer biomarkers Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0001558 [regulation of cell growth] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005925 [focal adhesion] GO:0006915 [apoptotic process] GO:0016021 [integral component of membrane] GO:0016505 [peptidase activator activity involved in apoptotic process] Show all	258 aa 29.5 kDa	Yes	0
EBAG9-202 ENSP00000477645 ENST00000620557	O00559 [Direct mapping] Receptor-binding cancer antigen expressed on SiSo cells A0A024R9E0 [Target identity:100%; Query identity:100%] Estrogen receptor binding site associated, antigen, 9, isoform CRA_a Show all	SPOCTOPUS predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins Cancer-related genes Candidate cancer biomarkers Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0001558 [regulation of cell growth] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005925 [focal adhesion] GO:0006915 [apoptotic process] GO:0016021 [integral component of membrane] GO:0016505 [peptidase activator activity involved in apoptotic process] Show all	213 aa 24.4 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.