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Granular cytoplasmic expression in several tissues, most abundant in gastrointestinal tract.
DATA RELIABILITY
Data reliability description
Antibody staining not consistent with RNA expression data. Secreted protein, tissue location of RNA and protein might differ and correlation is complex.
Mal, T-cell differentiation protein 2 (gene/pseudogene) (HGNC Symbol)
Entrez gene summary
This gene encodes a multispan transmembrane protein belonging to the MAL proteolipid family. The protein is a component of lipid rafts and, in polarized cells, it primarily localizes to endosomal structures beneath the apical membrane. It is required for transcytosis, an intracellular transport pathway used to deliver membrane-bound proteins and exogenous cargos from the basolateral to the apical surface. [provided by RefSeq, Jul 2008]
