Tissue expression of SH3GLB2 - Summary - The Human Protein Atlas

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SH3GLB2

TISSUE

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CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	SH3GLB2
Gene description	SH3-domain GRB2-like endophilin B2
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression at variable levels in most tissues.

DATA RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data.
Reliability score	Approved based on 2 antibodies. HPA021438 , HPA024734
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

N/A

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

Urinary bladder

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	SH3GLB2 (HGNC Symbol)
Synonyms	KIAA1848
Description	SH3-domain GRB2-like endophilin B2 (HGNC Symbol)
Entrez gene summary
Chromosome	9
Cytoband	q34.11
Chromosome location (bp)	129007036 - 129028303
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000148341 (version 83.38)
Entrez gene	56904
UniProt	Q9NR46 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NR46
Antibodypedia	SH3GLB2 antibodies

PROTEIN BROWSER

SH3GLB2-001	SH3GLB2-002	SH3GLB2-008	SH3GLB2-011	SH3GLB2-012

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SH3GLB2-001 ENSP00000361645 ENST00000372564	Q9NR46 [Direct mapping] Endophilin-B2 A0A024R896 [Target identity:100%; Query identity:100%] SH3-domain GRB2-like endophilin B2, isoform CRA_a Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] Show all	395 aa 44 kDa	No	0
SH3GLB2-002 ENSP00000361640 ENST00000372559	Q9NR46 [Direct mapping] Endophilin-B2 A0A024R896 [Target identity:100%; Query identity:100%] SH3-domain GRB2-like endophilin B2, isoform CRA_a Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] Show all	395 aa 44 kDa	No	0
SH3GLB2-008 ENSP00000361634 ENST00000372554	Q9NR46 [Direct mapping] Endophilin-B2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] Show all	404 aa 44.8 kDa	No	0
SH3GLB2-011 ENSP00000402566 ENST00000417224	B7ZC38 [Direct mapping] Endophilin-B2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] Show all	400 aa 44.4 kDa	No	0
SH3GLB2-012 ENSP00000388282 ENST00000416629	B7ZC39 [Direct mapping] Endophilin-B2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] Show all	374 aa 41.7 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.