Cell atlas - SLC43A1 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

SLC43A1

premium

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Golgi apparatus
	Plasma membrane
	Vesicles

Human cell
	Golgi Apparatus
	Plasma Membrane
	Vesicles

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	SLC43A1
Gene description	Solute carrier family 43 (amino acid system L transporter), member 1
Protein class	Predicted membrane proteins Transporters
Predicted localization	Membrane
Number of transcripts	5
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the plasma membrane, the Golgi apparatus & vesicles.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Golgi apparatus (approved), Vesicles (approved), Plasma membrane (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA018826
	SHOW MORE

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the plasma membrane, the Golgi apparatus & vesicles.

Main location

Golgi apparatus (approved), Vesicles (approved), Plasma membrane (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA018826	A-431	Vesicles
	HPA018826	A-431	Plasma membrane
	HPA018826	U-2 OS	Golgi apparatus
	HPA018826	U-2 OS	Vesicles
	HPA018826	U-251 MG	Golgi apparatus
	HPA018826	U-251 MG	Plasma membrane

GENE INFORMATION
Gene name	SLC43A1 (HGNC Symbol)
Synonyms	PB39, POV1, R00504
Description	Solute carrier family 43 (amino acid system L transporter), member 1 (HGNC Symbol)
Entrez gene summary	SLC43A1 belongs to the system L family of plasma membrane carrier proteins that transports large neutral amino acids (Babu et al., 2003 [PubMed 12930836]).[supplied by OMIM, Mar 2008]
Chromosome	11
Cytoband	q12.1
Chromosome location (bp)	57484534 - 57515786
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000149150 (version 83.38)
Entrez gene	8501
UniProt	O75387 (UniProt - Evidence at protein level)
neXtProt	NX_O75387
Antibodypedia	SLC43A1 antibodies

PROTEIN BROWSER

SLC43A1-001	SLC43A1-002	SLC43A1-003	SLC43A1-005	SLC43A1-010

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC43A1-001 ENSP00000278426 ENST00000278426	O75387 [Direct mapping] Large neutral amino acids transporter small subunit 3 A0A024R4Y3 [Target identity:100%; Query identity:100%] Solute carrier family 43, member 1, isoform CRA_b Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0006811 [ion transport] GO:0006865 [amino acid transport] GO:0015175 [neutral amino acid transmembrane transporter activity] GO:0015179 [L-amino acid transmembrane transporter activity] GO:0015804 [neutral amino acid transport] GO:0015807 [L-amino acid transport] GO:0016021 [integral component of membrane] GO:0055085 [transmembrane transport] GO:1902475 [L-alpha-amino acid transmembrane transport] Show all	559 aa 61.5 kDa	No	>9
SLC43A1-002 ENSP00000435673 ENST00000528450	O75387 [Direct mapping] Large neutral amino acids transporter small subunit 3 A0A024R4Y3 [Target identity:100%; Query identity:100%] Solute carrier family 43, member 1, isoform CRA_b Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0006811 [ion transport] GO:0006865 [amino acid transport] GO:0015175 [neutral amino acid transmembrane transporter activity] GO:0015179 [L-amino acid transmembrane transporter activity] GO:0015804 [neutral amino acid transport] GO:0016021 [integral component of membrane] GO:0055085 [transmembrane transport] GO:1902475 [L-alpha-amino acid transmembrane transport] Show all	559 aa 61.5 kDa	No	>9
SLC43A1-003 ENSP00000435486 ENST00000533263	E9PJT8 [Direct mapping] Large neutral amino acids transporter small subunit 3 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	110 aa 12.4 kDa	No	2
SLC43A1-005 ENSP00000435647 ENST00000533066	E9PJ68 [Direct mapping] Large neutral amino acids transporter small subunit 3 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	259 aa 28.4 kDa	No	6
SLC43A1-010 ENSP00000435803 ENST00000525764	H0YEH0 [Direct mapping] Large neutral amino acids transporter small subunit 3 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	186 aa 20.4 kDa	No	3

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.