Tissue expression of ARFGAP2 - Summary - The Human Protein Atlas

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ARFGAP2

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TISSUE

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CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	ARFGAP2
Gene description	ADP-ribosylation factor GTPase activating protein 2
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	11
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Ubiquitous cytoplasmic expression

DATA RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Supported based on 2 antibodies. HPA016649 , HPA018152
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	ARFGAP2 (HGNC Symbol)
Synonyms	FLJ14576, IRZ, Zfp289, ZNF289
Description	ADP-ribosylation factor GTPase activating protein 2 (HGNC Symbol)
Entrez gene summary
Chromosome	11
Cytoband	p11.2
Chromosome location (bp)	47164299 - 47177125
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000149182 (version 83.38)
Entrez gene	84364
UniProt	Q8N6H7 (UniProt - Evidence at protein level)
neXtProt	NX_Q8N6H7
Antibodypedia	ARFGAP2 antibodies

PROTEIN BROWSER

ARFGAP2-001	ARFGAP2-002	ARFGAP2-015	ARFGAP2-017	ARFGAP2-021	ARFGAP2-023	ARFGAP2-026	ARFGAP2-027	ARFGAP2-201	ARFGAP2-202	ARFGAP2-203

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ARFGAP2-001 ENSP00000434442 ENST00000524782	Q8N6H7 [Direct mapping] ADP-ribosylation factor GTPase-activating protein 2 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0005096 [GTPase activator activity] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0015031 [protein transport] GO:0016192 [vesicle-mediated transport] GO:0043547 [positive regulation of GTPase activity] GO:0046872 [metal ion binding] Show all	521 aa 56.7 kDa	No	0
ARFGAP2-002 ENSP00000431684 ENST00000528444	E9PK28 [Direct mapping] ADP-ribosylation factor GTPase-activating protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005096 [GTPase activator activity] GO:0043547 [positive regulation of GTPase activity] Show all	239 aa 26.1 kDa	No	0
ARFGAP2-015 ENSP00000434809 ENST00000525314	E9PN48 [Direct mapping] ADP-ribosylation factor GTPase-activating protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005096 [GTPase activator activity] GO:0005737 [cytoplasm] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0043547 [positive regulation of GTPase activity] Show all	252 aa 27.1 kDa	No	0
ARFGAP2-017 ENSP00000434433 ENST00000527927	E9PQP3 [Direct mapping] ADP-ribosylation factor GTPase-activating protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005096 [GTPase activator activity] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0005794 [Golgi apparatus] GO:0043547 [positive regulation of GTPase activity] Show all	274 aa 30.6 kDa	No	0
ARFGAP2-021 ENSP00000435488 ENST00000530596	E9PJT7 [Direct mapping] ADP-ribosylation factor GTPase-activating protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005096 [GTPase activator activity] GO:0043547 [positive regulation of GTPase activity] Show all	173 aa 19.4 kDa	No	0
ARFGAP2-023 ENSP00000431939 ENST00000525398	E9PIY6 [Direct mapping] ADP-ribosylation factor GTPase-activating protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005096 [GTPase activator activity] GO:0005737 [cytoplasm] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0043547 [positive regulation of GTPase activity] Show all	327 aa 36.1 kDa	No	0
ARFGAP2-026 ENSP00000437305 ENST00000526342	E9PMU9 [Direct mapping] ADP-ribosylation factor GTPase-activating protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005096 [GTPase activator activity] GO:0043547 [positive regulation of GTPase activity] Show all	156 aa 17.4 kDa	No	0
ARFGAP2-027 ENSP00000434022 ENST00000527776	H0YDN9 [Direct mapping] ADP-ribosylation factor GTPase-activating protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		237 aa 25.7 kDa	No	0
ARFGAP2-201 ENSP00000400226 ENST00000426335	G5E9L0 [Direct mapping] ADP-ribosylation factor GTPase-activating protein 2 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005096 [GTPase activator activity] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0005794 [Golgi apparatus] GO:0043547 [positive regulation of GTPase activity] Show all	493 aa 53.5 kDa	No	0
ARFGAP2-202 ENSP00000486339 ENST00000627920	A0A0D9SF70 [Direct mapping] ADP-ribosylation factor GTPase-activating protein 2; Zinc finger protein 289, ID1 regulated, isoform CRA_d Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005096 [GTPase activator activity] GO:0043547 [positive regulation of GTPase activity] Show all	385 aa 42.2 kDa	No	0
ARFGAP2-203 ENSP00000486229 ENST00000629231	E9PM18 [Direct mapping] ADP-ribosylation factor GTPase-activating protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005096 [GTPase activator activity] GO:0043547 [positive regulation of GTPase activity] Show all	70 aa 7.7 kDa	No	0

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The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.