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ABCB9
  • TISSUE

  • premium

    CELL

  • PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

ABCB9

Gene description

ATP-binding cassette, sub-family B (MDR/TAP), member 9

Protein class

Predicted intracellular proteins
Predicted membrane proteins
Transporters

Predicted localization

Intracellular,Membrane

Number of transcripts

16
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Tissue enhanced (testis)
GTEx:Mixed
FANTOM5:Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in most tissues.

DATA RELIABILITY

Data reliability
description

Antibody staining mainly not consistent with RNA expression data.

Reliability score

Approved based on 2 antibodies.
HPA035114 , CAB033052
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (testis)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

ABCB9 (HGNC Symbol)

Synonyms

EST122234

Description

ATP-binding cassette, sub-family B (MDR/TAP), member 9 (HGNC Symbol)

Entrez gene summary

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This family member functions in the translocation of peptides from the cytosol into the lysosomal lumen. Alternative splicing of this gene results in distinct isoforms which are likely to have different substrate specificities. [provided by RefSeq, Jul 2011]

Chromosome

12

Cytoband

q24.31

Chromosome location (bp)

122920951 - 122981649

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000150967 (version 83.38)

Entrez gene

23457

UniProt

Q9NP78 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NP78

Antibodypedia

ABCB9 antibodies

PROTEIN BROWSER

«
ABCB9-001
ABCB9-002
ABCB9-003
ABCB9-004
ABCB9-005
ABCB9-006
ABCB9-011
ABCB9-012
ABCB9-013
ABCB9-014
ABCB9-015
ABCB9-016
ABCB9-018
ABCB9-019
ABCB9-201
ABCB9-202
»

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ABCB9-001
ENSP00000440288
ENST00000542678
Q9NP78 [Direct mapping]
ATP-binding cassette sub-family B member 9
A0A024RBU1 [Target identity:100%; Query identity:100%]
ATP-binding cassette, sub-family B (MDR/TAP), member 9, isoform CRA_f
Show all
Transporters
   Primary Active Transporters
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   8TM proteins predicted by MDM
Show all
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005764 [lysosome]
GO:0005765 [lysosomal membrane]
GO:0006810 [transport]
GO:0008152 [metabolic process]
GO:0015031 [protein transport]
GO:0015421 [oligopeptide-transporting ATPase activity]
GO:0015440 [peptide-transporting ATPase activity]
GO:0015833 [peptide transport]
GO:0016021 [integral component of membrane]
GO:0016887 [ATPase activity]
GO:0022891 [substrate-specific transmembrane transporter activity]
GO:0030176 [integral component of endoplasmic reticulum membrane]
GO:0035672 [oligopeptide transmembrane transport]
GO:0042626 [ATPase activity, coupled to transmembrane movement of substances]
GO:0042803 [protein homodimerization activity]
GO:0055085 [transmembrane transport]
Show all
766 aa
84.5 kDa
No 8
ABCB9-002
ENSP00000376234
ENST00000392439
Q9NP78 [Direct mapping]
ATP-binding cassette sub-family B member 9
A0A024RBU1 [Target identity:100%; Query identity:100%]
ATP-binding cassette, sub-family B (MDR/TAP), member 9, isoform CRA_f
Show all
Transporters
   Primary Active Transporters
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   8TM proteins predicted by MDM
Show all
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005764 [lysosome]
GO:0005765 [lysosomal membrane]
GO:0006810 [transport]
GO:0008152 [metabolic process]
GO:0015031 [protein transport]
GO:0015421 [oligopeptide-transporting ATPase activity]
GO:0015440 [peptide-transporting ATPase activity]
GO:0015833 [peptide transport]
GO:0016021 [integral component of membrane]
GO:0016887 [ATPase activity]
GO:0022891 [substrate-specific transmembrane transporter activity]
GO:0030176 [integral component of endoplasmic reticulum membrane]
GO:0035672 [oligopeptide transmembrane transport]
GO:0042626 [ATPase activity, coupled to transmembrane movement of substances]
GO:0042803 [protein homodimerization activity]
GO:0055085 [transmembrane transport]
Show all
766 aa
84.5 kDa
No 8
ABCB9-003
ENSP00000441734
ENST00000540285
Q9NP78 [Direct mapping]
ATP-binding cassette sub-family B member 9
Show all
Transporters
   Primary Active Transporters
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   7TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005764 [lysosome]
GO:0005765 [lysosomal membrane]
GO:0006810 [transport]
GO:0008152 [metabolic process]
GO:0015031 [protein transport]
GO:0015421 [oligopeptide-transporting ATPase activity]
GO:0015440 [peptide-transporting ATPase activity]
GO:0015833 [peptide transport]
GO:0016021 [integral component of membrane]
GO:0016887 [ATPase activity]
GO:0022891 [substrate-specific transmembrane transporter activity]
GO:0030176 [integral component of endoplasmic reticulum membrane]
GO:0035672 [oligopeptide transmembrane transport]
GO:0042626 [ATPase activity, coupled to transmembrane movement of substances]
GO:0042803 [protein homodimerization activity]
GO:0055085 [transmembrane transport]
Show all
703 aa
77.5 kDa
No 7
ABCB9-004
ENSP00000280560
ENST00000280560
Q9NP78 [Direct mapping]
ATP-binding cassette sub-family B member 9
A0A024RBU1 [Target identity:100%; Query identity:100%]
ATP-binding cassette, sub-family B (MDR/TAP), member 9, isoform CRA_f
Show all
Transporters
   Primary Active Transporters
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   8TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005764 [lysosome]
GO:0005765 [lysosomal membrane]
GO:0006810 [transport]
GO:0008152 [metabolic process]
GO:0015031 [protein transport]
GO:0015421 [oligopeptide-transporting ATPase activity]
GO:0015440 [peptide-transporting ATPase activity]
GO:0015833 [peptide transport]
GO:0016021 [integral component of membrane]
GO:0016887 [ATPase activity]
GO:0022891 [substrate-specific transmembrane transporter activity]
GO:0030176 [integral component of endoplasmic reticulum membrane]
GO:0035672 [oligopeptide transmembrane transport]
GO:0042626 [ATPase activity, coupled to transmembrane movement of substances]
GO:0042803 [protein homodimerization activity]
GO:0055085 [transmembrane transport]
Show all
766 aa
84.5 kDa
No 8
ABCB9-005
ENSP00000456375
ENST00000442833
Q9NP78 [Direct mapping]
ATP-binding cassette sub-family B member 9
Show all
Transporters
   Primary Active Transporters
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   8TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005764 [lysosome]
GO:0005765 [lysosomal membrane]
GO:0006810 [transport]
GO:0008152 [metabolic process]
GO:0015031 [protein transport]
GO:0015421 [oligopeptide-transporting ATPase activity]
GO:0015440 [peptide-transporting ATPase activity]
GO:0015833 [peptide transport]
GO:0016021 [integral component of membrane]
GO:0016887 [ATPase activity]
GO:0022891 [substrate-specific transmembrane transporter activity]
GO:0030176 [integral component of endoplasmic reticulum membrane]
GO:0035672 [oligopeptide transmembrane transport]
GO:0042626 [ATPase activity, coupled to transmembrane movement of substances]
GO:0042803 [protein homodimerization activity]
GO:0055085 [transmembrane transport]
Show all
683 aa
75.4 kDa
No 8
ABCB9-006
ENSP00000456813
ENST00000344275
Q9NP78 [Direct mapping]
ATP-binding cassette sub-family B member 9
Show all
Transporters
   Primary Active Transporters
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   8TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005764 [lysosome]
GO:0005765 [lysosomal membrane]
GO:0006810 [transport]
GO:0008152 [metabolic process]
GO:0015031 [protein transport]
GO:0015421 [oligopeptide-transporting ATPase activity]
GO:0015440 [peptide-transporting ATPase activity]
GO:0015833 [peptide transport]
GO:0016021 [integral component of membrane]
GO:0016887 [ATPase activity]
GO:0022891 [substrate-specific transmembrane transporter activity]
GO:0030176 [integral component of endoplasmic reticulum membrane]
GO:0035672 [oligopeptide transmembrane transport]
GO:0042626 [ATPase activity, coupled to transmembrane movement of substances]
GO:0042803 [protein homodimerization activity]
GO:0055085 [transmembrane transport]
Show all
681 aa
75.3 kDa
No 8
ABCB9-011
ENSP00000443382
ENST00000543935
F5H5I5 [Direct mapping]
ATP-binding cassette sub-family B member 9
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Show all
GO:0016021 [integral component of membrane]
Show all
65 aa
7.4 kDa
No 1
ABCB9-012
ENSP00000441086
ENST00000540971
F5GX86 [Direct mapping]
ATP-binding cassette sub-family B member 9
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   3TM proteins predicted by MDM
Show all
GO:0005524 [ATP binding]
GO:0006810 [transport]
GO:0016021 [integral component of membrane]
GO:0042626 [ATPase activity, coupled to transmembrane movement of substances]
GO:0055085 [transmembrane transport]
Show all
182 aa
20.3 kDa
No 3
ABCB9-013
ENSP00000440138
ENST00000541424
F5GXZ5 [Direct mapping]
ATP-binding cassette sub-family B member 9
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   2TM proteins predicted by MDM
Show all
GO:0005524 [ATP binding]
GO:0006810 [transport]
GO:0016021 [integral component of membrane]
GO:0042626 [ATPase activity, coupled to transmembrane movement of substances]
GO:0055085 [transmembrane transport]
Show all
146 aa
16.3 kDa
No 2
ABCB9-014
ENSP00000443433
ENST00000536976
F5H5F9 [Direct mapping]
ATP-binding cassette sub-family B member 9
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   4TM proteins predicted by MDM
Show all
GO:0005524 [ATP binding]
GO:0006810 [transport]
GO:0016021 [integral component of membrane]
GO:0042626 [ATPase activity, coupled to transmembrane movement of substances]
GO:0055085 [transmembrane transport]
Show all
222 aa
25.2 kDa
No 4
ABCB9-015
ENSP00000443224
ENST00000546077
F5H5Q0 [Direct mapping]
ATP-binding cassette sub-family B member 9
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Show all
GO:0005524 [ATP binding]
GO:0006810 [transport]
GO:0016021 [integral component of membrane]
GO:0042626 [ATPase activity, coupled to transmembrane movement of substances]
GO:0055085 [transmembrane transport]
Show all
115 aa
13 kDa
No 1
ABCB9-016
ENSP00000440244
ENST00000542448
F5GYI2 [Direct mapping]
ATP-binding cassette sub-family B member 9
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   2TM proteins predicted by MDM
Show all
GO:0005524 [ATP binding]
GO:0006810 [transport]
GO:0008152 [metabolic process]
GO:0016021 [integral component of membrane]
GO:0016887 [ATPase activity]
GO:0042626 [ATPase activity, coupled to transmembrane movement of substances]
GO:0055085 [transmembrane transport]
Show all
260 aa
28.8 kDa
No 2
ABCB9-018
ENSP00000442281
ENST00000546289
F5H7U2 [Direct mapping]
ATP-binding cassette sub-family B member 9
Show all
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Show all
GO:0005524 [ATP binding]
GO:0006810 [transport]
GO:0008152 [metabolic process]
GO:0016021 [integral component of membrane]
GO:0016887 [ATPase activity]
GO:0042626 [ATPase activity, coupled to transmembrane movement of substances]
GO:0055085 [transmembrane transport]
Show all
277 aa
29.8 kDa
No 0
ABCB9-019
ENSP00000444834
ENST00000545373
F5H4Y2 [Direct mapping]
ATP-binding cassette sub-family B member 9
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   # TM segments-based
   2TM proteins predicted by MDM
Show all
GO:0005524 [ATP binding]
GO:0006810 [transport]
GO:0008152 [metabolic process]
GO:0016021 [integral component of membrane]
GO:0016887 [ATPase activity]
GO:0042626 [ATPase activity, coupled to transmembrane movement of substances]
GO:0055085 [transmembrane transport]
Show all
156 aa
16.7 kDa
No 2
ABCB9-201
ENSP00000280559
ENST00000346530
Q9NP78 [Direct mapping]
ATP-binding cassette sub-family B member 9
Show all
Transporters
   Primary Active Transporters
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   7TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005764 [lysosome]
GO:0005765 [lysosomal membrane]
GO:0006810 [transport]
GO:0008152 [metabolic process]
GO:0015031 [protein transport]
GO:0015421 [oligopeptide-transporting ATPase activity]
GO:0015440 [peptide-transporting ATPase activity]
GO:0015833 [peptide transport]
GO:0016021 [integral component of membrane]
GO:0016887 [ATPase activity]
GO:0022891 [substrate-specific transmembrane transporter activity]
GO:0030176 [integral component of endoplasmic reticulum membrane]
GO:0035672 [oligopeptide transmembrane transport]
GO:0042626 [ATPase activity, coupled to transmembrane movement of substances]
GO:0042803 [protein homodimerization activity]
GO:0055085 [transmembrane transport]
Show all
723 aa
79.8 kDa
No 7
ABCB9-202
ENSP00000394898
ENST00000442028
Q6P2Q0 [Direct mapping]
ABCB9 protein; ATP-binding cassette sub-family B member 9
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   8TM proteins predicted by MDM
Show all
GO:0005524 [ATP binding]
GO:0006810 [transport]
GO:0008152 [metabolic process]
GO:0016021 [integral component of membrane]
GO:0016887 [ATPase activity]
GO:0042626 [ATPase activity, coupled to transmembrane movement of substances]
GO:0055085 [transmembrane transport]
Show all
769 aa
84.8 kDa
No 8

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