Fields »
ABOUT
HELP
BLOG
GEMIN6

GENERAL INFORMATION

Gene name

 GEMIN6

Gene description

 Gem (nuclear organelle) associated protein 6

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 General cytoplasmic expression.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Pending external verification.

Reliability score

 Approved based on 1 antibody.
HPA035726
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Pancreas

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 GEMIN6 (HGNC Symbol)

Synonyms

 FLJ23459

Description

 Gem (nuclear organelle) associated protein 6 (HGNC Symbol)

Entrez gene summary

 GEMIN6 is part of a large macromolecular complex, localized to both the cytoplasm and the nucleus, that plays a role in the cytoplasmic assembly of small nuclear ribonucleoproteins (snRNPs). Other members of this complex include SMN (MIM 600354), GEMIN2 (SIP1; MIM 602595), GEMIN3 (DDX20; MIM 606168), GEMIN4 (MIM 606969), and GEMIN5 (MIM 607005).[supplied by OMIM, Jul 2002]

Chromosome

 2

Cytoband

 p22.1

Chromosome location (bp)

 38751534 - 38785000

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000152147 (version 83.38)

Entrez gene

 79833

UniProt

 Q8WXD5 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8WXD5

Antibodypedia

 GEMIN6 antibodies

PROTEIN BROWSER
GEMIN6-001
GEMIN6-002
GEMIN6-003

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
GEMIN6-001
ENSP00000281950
ENST00000281950
Q8WXD5 [Direct mapping]
Gem-associated protein 6
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000245 [spliceosomal complex assembly]
GO:0000387 [spliceosomal snRNP assembly]
GO:0000398 [mRNA splicing, via spliceosome]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0010467 [gene expression]
GO:0016604 [nuclear body]
GO:0032797 [SMN complex]
GO:0034660 [ncRNA metabolic process]
GO:0034719 [SMN-Sm protein complex]
GO:0097504 [Gemini of coiled bodies]
Show all
 167 aa
18.8 kDa 		No 0
GEMIN6-002
ENSP00000386613
ENST00000409566
B8ZZ85 [Direct mapping]
Gem (Nuclear organelle) associated protein 6, isoform CRA_b; Gem-associated protein 6
Show all
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000245 [spliceosomal complex assembly]
GO:0005634 [nucleus]
Show all
 111 aa
12.4 kDa 		No 0
GEMIN6-003
ENSP00000387191
ENST00000409011
B9A037 [Direct mapping]
Gem-associated protein 6
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000245 [spliceosomal complex assembly]
GO:0005634 [nucleus]
Show all
 69 aa
7.9 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.