Cell atlas - PELO - The Human Protein Atlas

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PELO

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleoli fibrillar center

Human cell
	Nucleoli

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GENERAL INFORMATION
Gene name	PELO
Gene description	Pelota homolog (Drosophila)
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleoli (fibrillar center).
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoli fibrillar center (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA031458
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleoli (fibrillar center).

Main location

Nucleoli fibrillar center (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA031458	A-431	Nucleoli fibrillar center
	HPA031458	U-2 OS	Nucleoli fibrillar center
	HPA031458	U-251 MG	Nucleoli fibrillar center

GENE INFORMATION
Gene name	PELO
Synonyms
Description	Pelota homolog (Drosophila) (HGNC Symbol)
Entrez gene summary	This gene encodes a protein which contains a conserved nuclear localization signal. The encoded protein may have a role in spermatogenesis, cell cycle control, and in meiotic cell division. [provided by RefSeq, Jul 2008]
Chromosome	5
Cytoband	q11.2
Chromosome location (bp)	52787940 - 52804046
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000152684 (version 83.38)
Entrez gene	53918
UniProt	Q9BRX2 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BRX2
Antibodypedia	PELO antibodies

PROTEIN BROWSER

PELO-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PELO-001 ENSP00000274311 ENST00000274311	Q9BRX2 [Direct mapping] Protein pelota homolog Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004519 [endonuclease activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0007049 [cell cycle] GO:0008283 [cell proliferation] GO:0046872 [metal ion binding] GO:0051276 [chromosome organization] GO:0051301 [cell division] GO:0070481 [nuclear-transcribed mRNA catabolic process, non-stop decay] GO:0070966 [nuclear-transcribed mRNA catabolic process, no-go decay] GO:0071025 [RNA surveillance] GO:0090305 [nucleic acid phosphodiester bond hydrolysis] Show all	385 aa 43.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.