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PELO

GENERAL INFORMATION

Gene name

 PELO

Gene description

 Pelota homolog (Drosophila)

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Cytoplasmic and nuclear expression in most tissues.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Pending external verification.

Reliability score

 Approved based on 1 antibody.
HPA031458
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PROGNOSTIC SUMMARY
Prognostic marker in breast cancer (unfavourable).
Breast cancer p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA031458

GENE INFORMATION

Gene name

 PELO

Synonyms

Description

 Pelota homolog (Drosophila) (HGNC Symbol)

Entrez gene summary

 This gene encodes a protein which contains a conserved nuclear localization signal. The encoded protein may have a role in spermatogenesis, cell cycle control, and in meiotic cell division. [provided by RefSeq, Jul 2008]

Chromosome

 5

Cytoband

 q11.2

Chromosome location (bp)

 52787940 - 52804046

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000152684 (version 83.38)

Entrez gene

 53918

UniProt

 Q9BRX2 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9BRX2

Antibodypedia

 PELO antibodies

PROTEIN BROWSER
PELO-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
PELO-001
ENSP00000274311
ENST00000274311
Q9BRX2 [Direct mapping]
Protein pelota homolog
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0004519 [endonuclease activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0007049 [cell cycle]
GO:0008283 [cell proliferation]
GO:0046872 [metal ion binding]
GO:0051276 [chromosome organization]
GO:0051301 [cell division]
GO:0070481 [nuclear-transcribed mRNA catabolic process, non-stop decay]
GO:0070966 [nuclear-transcribed mRNA catabolic process, no-go decay]
GO:0071025 [RNA surveillance]
GO:0090305 [nucleic acid phosphodiester bond hydrolysis]
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 385 aa
43.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.