Expression of SCOC in cancer - Summary - The Human Protein Atlas

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SCOC

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	SCOC
Gene description	Short coiled-coil protein
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	11
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in most tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Approved based on 1 antibody. HPA070321
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable).
Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA070321

GENE INFORMATION
Gene name	SCOC (HGNC Symbol)
Synonyms	HRIHFB2072, SCOCO
Description	Short coiled-coil protein (HGNC Symbol)
Entrez gene summary	This gene encodes a short coiled-coiled domain-containing protein that localizes to the Golgi apparatus. The encoded protein interacts with ADP-ribosylation factor-like proteins. Pseudogenes of this gene are found on chromosomes 1 and 14. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]
Chromosome	4
Cytoband	q31.1
Chromosome location (bp)	140257286 - 140385726
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000153130 (version 83.38)
Entrez gene	60592
UniProt	Q9UIL1 (UniProt - Evidence at protein level)
neXtProt	NX_Q9UIL1
Antibodypedia	SCOC antibodies

PROTEIN BROWSER

SCOC-001	SCOC-002	SCOC-003	SCOC-004	SCOC-005	SCOC-006	SCOC-007	SCOC-009	SCOC-010	SCOC-201	SCOC-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SCOC-001 ENSP00000477352 ENST00000608372	Q9UIL1 [Direct mapping] Short coiled-coil protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0005515 [protein binding] GO:0005768 [endosome] GO:0005802 [trans-Golgi network] GO:0005829 [cytosol] GO:0016239 [positive regulation of macroautophagy] GO:0061635 [regulation of protein complex stability] Show all	159 aa 18 kDa	No	0
SCOC-002 ENSP00000345262 ENST00000338517	Q9UIL1 [Direct mapping] Short coiled-coil protein Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0005515 [protein binding] GO:0005768 [endosome] GO:0005802 [trans-Golgi network] GO:0005829 [cytosol] GO:0016239 [positive regulation of macroautophagy] GO:0061635 [regulation of protein complex stability] Show all	122 aa 13.9 kDa	No	0
SCOC-003 ENSP00000377755 ENST00000394205	Q9UIL1 [Direct mapping] Short coiled-coil protein Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0005515 [protein binding] GO:0005768 [endosome] GO:0005802 [trans-Golgi network] GO:0005829 [cytosol] GO:0016239 [positive regulation of macroautophagy] GO:0061635 [regulation of protein complex stability] Show all	122 aa 13.9 kDa	No	0
SCOC-004 ENSP00000426649 ENST00000506597	Q9UIL1 [Direct mapping] Short coiled-coil protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0005515 [protein binding] GO:0005768 [endosome] GO:0005802 [trans-Golgi network] GO:0005829 [cytosol] GO:0016239 [positive regulation of macroautophagy] GO:0061635 [regulation of protein complex stability] Show all	131 aa 14.8 kDa	No	0
SCOC-005 ENSP00000424688 ENST00000510586	A0A0C4DGB0 [Direct mapping] Short coiled-coil protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		82 aa 9.4 kDa	No	0
SCOC-006 ENSP00000424605 ENST00000512749	A0A0C4DGB0 [Direct mapping] Short coiled-coil protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		82 aa 9.4 kDa	No	0
SCOC-007 ENSP00000421355 ENST00000502535	A0A0C4DGB0 [Direct mapping] Short coiled-coil protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		82 aa 9.4 kDa	No	0
SCOC-009 ENSP00000426810 ENST00000506322	A0A0C4DGB0 [Direct mapping] Short coiled-coil protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		82 aa 9.4 kDa	No	0
SCOC-010 ENSP00000377751 ENST00000394201	A0A0C4DGB0 [Direct mapping] Short coiled-coil protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		82 aa 9.4 kDa	No	0
SCOC-201 ENSP00000377753 ENST00000394203	Q9UIL1 [Direct mapping] Short coiled-coil protein Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0005515 [protein binding] GO:0005768 [endosome] GO:0005802 [trans-Golgi network] GO:0005829 [cytosol] GO:0016239 [positive regulation of macroautophagy] GO:0061635 [regulation of protein complex stability] Show all	122 aa 13.9 kDa	No	0
SCOC-202 ENSP00000477812 ENST00000614192	Q9UIL1 [Direct mapping] Short coiled-coil protein Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0005515 [protein binding] GO:0005768 [endosome] GO:0005802 [trans-Golgi network] GO:0005829 [cytosol] GO:0016239 [positive regulation of macroautophagy] GO:0061635 [regulation of protein complex stability] Show all	159 aa 18 kDa	No	0

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The Human Protein Atlas

The Human Protein Atlas project is funded
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