Cell atlas - RGPD3 - The Human Protein Atlas

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RGPD3

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nuclear membrane
	Vesicles

Human cell
	Nuclear membrane
	Vesicles

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GENERAL INFORMATION
Gene name	RGPD3
Gene description	RANBP2-like and GRIP domain containing 3
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nuclear membrane & vesicles. Caution: Based on antibodies targeting proteins from multiple genes.
RNA cell category	Group enriched (MOLT-4, HEL, RPMI-8226)
Protein evidence	Evidence at transcript level
Main location	Localized to the Nuclear membrane (approved), Vesicles (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA067564
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Group enriched (MOLT-4, HEL, RPMI-8226) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nuclear membrane & vesicles. Caution: Based on antibodies targeting proteins from multiple genes.

Main location

Nuclear membrane (approved), Vesicles (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA067564	CACO-2	Nuclear membrane
	HPA067564	CACO-2	Vesicles
	HPA067564	RT4	Nuclear membrane
	HPA067564	RT4	Vesicles
	HPA067564	U-2 OS	Nuclear membrane
	HPA067564	U-2 OS	Vesicles

GENE INFORMATION
Gene name	RGPD3 (HGNC Symbol)
Synonyms	RGP3
Description	RANBP2-like and GRIP domain containing 3 (HGNC Symbol)
Entrez gene summary	This gene is located in a cluster of Ran-binding protein related genes on chromosome 2 which arose through duplication in primates. The encoded protein contains an N-terminal TPR (tetratricopeptide repeat) domain, two Ran-binding domains, and a C-terminal GRIP domain (golgin-97, RanBP2alpha, Imh1p and p230/golgin-245) domain. [provided by RefSeq, Sep 2011]
Chromosome	2
Cytoband	q12.2
Chromosome location (bp)	106391290 - 106468376
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000153165 (version 83.38)
Entrez gene	653489
UniProt	A6NKT7 (UniProt - Inferred from homology)
neXtProt	NX_A6NKT7
Antibodypedia	RGPD3 antibodies

PROTEIN BROWSER

RGPD3-002	RGPD3-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RGPD3-002 ENSP00000386588 ENST00000409886	A6NKT7 [Direct mapping] RanBP2-like and GRIP domain-containing protein 3 Show all	MEMSAT3 predicted membrane proteins Predicted intracellular proteins Show all	GO:0000042 [protein targeting to Golgi] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0046907 [intracellular transport] Show all	1758 aa 197.5 kDa	No	0
RGPD3-201 ENSP00000303659 ENST00000304514	J3KNE0 [Direct mapping] RanBP2-like and GRIP domain-containing protein 3 Show all	MEMSAT3 predicted membrane proteins Predicted intracellular proteins Show all	GO:0000042 [protein targeting to Golgi] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0046907 [intracellular transport] Show all	1760 aa 197.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.