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GAL3ST2

GENERAL INFORMATION

Gene name

 GAL3ST2

Gene description

 Galactose-3-O-sulfotransferase 2

Protein class

 Predicted secreted proteins

Predicted localization

 Secreted

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Group enriched (colon, rectum)
GTEx:Tissue enhanced (colon)
FANTOM5:Group enriched (appendix, colon, gallbladder, salivary gland, tonsil)

Protein evidence

 Evidence at protein level

Protein expression

 Selective cytoplasmic expression with a granular pattern in colon and rectum

DATA RELIABILITY

Data reliability
description

 Antibody staining consistent with RNA expression data.

Reliability score

 Supported based on 1 antibody.
HPA071809
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Appendix

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (colon, rectum)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (colon)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (appendix, colon, gallbladder, salivary gland, tonsil)

GENE INFORMATION

Gene name

 GAL3ST2 (HGNC Symbol)

Synonyms

 GP3ST

Description

 Galactose-3-O-sulfotransferase 2 (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the galactose-3-O-sulfotransferase protein family. The product of this gene catalyzes sulfonation by transferring a sulfate group to the hydroxyl at C-3 of nonreducing beta-galactosyl residues, and it can act on both type 1 and type 2 (Galbeta 1-3/1-4GlcNAc-R) oligosaccharides with similar efficiencies, and on core 1 glycans. This enzyme has been implicated in tumor metastasis processes. This gene is different from the GAL3ST3 gene located on chromosome 11, which has also been referred to as GAL3ST2 and encodes a related enzyme with distinct tissue distribution and substrate specificities, compared to galactose-3-O-sulfotransferase 2. [provided by RefSeq, Jul 2008]

Chromosome

 2

Cytoband

 q37.3

Chromosome location (bp)

 241776825 - 241804208

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000154252 (version 83.38)

Entrez gene

 64090

UniProt

 Q9H3Q3 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9H3Q3

Antibodypedia

 GAL3ST2 antibodies

PROTEIN BROWSER
GAL3ST2-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
GAL3ST2-001
ENSP00000192314
ENST00000192314
Q9H3Q3 [Direct mapping]
Galactose-3-O-sulfotransferase 2
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   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
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GO:0001733 [galactosylceramide sulfotransferase activity]
GO:0005515 [protein binding]
GO:0008146 [sulfotransferase activity]
GO:0008150 [biological_process]
GO:0009058 [biosynthetic process]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0032580 [Golgi cisterna membrane]
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 398 aa
46.1 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.