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CCSAP

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GENERAL INFORMATION

Gene name

 CCSAP

Gene description

 Centriole, cilia and spindle-associated protein

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

Summary

 Mainly localized to the nucleoplasm. In addition localized to the cytokinetic bridge.

RNA cell category

 Expressed in all

Protein evidence

 Evidence at protein level

Main location

 Localized to the Nucleoplasm (uncertain)

Additional location

 In addition localized to the Cytokinetic bridge (uncertain)

Single-cell variation

 Single-cell variation in protein expression observed.

Cell cycle dependency

 Cell cycle dependent expression determined by biological definition

DATA RELIABILITY

Reliability score

 Uncertain based on 2 antibodies.
HPA028402 , HPA043443
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ASSAYS
RNA expression
Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

HUMAN CELLS

Summary

 Mainly localized to the nucleoplasm. In addition localized to the cytokinetic bridge.

Main location

 Nucleoplasm (uncertain)

Additional location

 Cytokinetic bridge (uncertain)

 

 

 
Toggle channels
Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location

Single-cell variation

Cell cycle dependent variation
HPA028402 A-431 Nucleoplasm
HPA028402 U-2 OS Nucleus
Cytokinetic bridge Intensity Intensity
HPA028402 U-251 MG Nucleoplasm
HPA043443 A-431 Nucleoplasm
HPA043443 U-2 OS Nucleoplasm
Plasma membrane
HPA043443 U-251 MG Nucleoplasm

CELL CYCLE

Summary

 Expression has cell cycle dependency according to biological definition

Intensity variation

 Cytokinetic bridge

GENE INFORMATION

Gene name

 CCSAP (HGNC Symbol)

Synonyms

 C1orf96, CSAP, FLJ41471

Description

 Centriole, cilia and spindle-associated protein (HGNC Symbol)

Entrez gene summary

Chromosome

 1

Cytoband

 q42.13

Chromosome location (bp)

 229321005 - 229343294

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000154429 (version 83.38)

Entrez gene

 126731

UniProt

 Q6IQ19 (UniProt - Evidence at protein level)

neXtProt

 NX_Q6IQ19

Antibodypedia

 CCSAP antibodies

PROTEIN BROWSER
CCSAP-001
CCSAP-003
CCSAP-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CCSAP-001
ENSP00000355648
ENST00000366687
Q6IQ19 [Direct mapping]
Centriole, cilia and spindle-associated protein
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005813 [centrosome]
GO:0005814 [centriole]
GO:0005819 [spindle]
GO:0005929 [cilium]
GO:0005930 [axoneme]
GO:0007275 [multicellular organismal development]
GO:0030424 [axon]
GO:0035869 [ciliary transition zone]
GO:0036064 [ciliary basal body]
GO:0045995 [regulation of embryonic development]
GO:0060296 [regulation of cilium beat frequency involved in ciliary motility]
Show all
 270 aa
30.2 kDa 		No 0
CCSAP-003
ENSP00000355647
ENST00000366686
Q6IQ19 [Direct mapping]
Centriole, cilia and spindle-associated protein
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005813 [centrosome]
GO:0005814 [centriole]
GO:0005819 [spindle]
GO:0005929 [cilium]
GO:0005930 [axoneme]
GO:0007275 [multicellular organismal development]
GO:0030424 [axon]
GO:0035869 [ciliary transition zone]
GO:0036064 [ciliary basal body]
GO:0045995 [regulation of embryonic development]
GO:0060296 [regulation of cilium beat frequency involved in ciliary motility]
Show all
 156 aa
17.8 kDa 		No 0
CCSAP-201
ENSP00000284617
ENST00000284617
Q6IQ19 [Direct mapping]
Centriole, cilia and spindle-associated protein
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005813 [centrosome]
GO:0005814 [centriole]
GO:0005819 [spindle]
GO:0005929 [cilium]
GO:0005930 [axoneme]
GO:0007275 [multicellular organismal development]
GO:0030424 [axon]
GO:0035869 [ciliary transition zone]
GO:0036064 [ciliary basal body]
GO:0045995 [regulation of embryonic development]
GO:0060296 [regulation of cilium beat frequency involved in ciliary motility]
Show all
 270 aa
30.2 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.