Cell atlas - MMP21 - The Human Protein Atlas

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MMP21

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	MMP21
Gene description	Matrix metallopeptidase 21
Protein class	Enzymes FDA approved drug targets Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Not detected
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Not detected Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	MMP21
Synonyms
Description	Matrix metallopeptidase 21 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the matrix metalloproteinase family. Proteins in this family are involved in the breakdown of extracellular matrix for both normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, and disease processes, such as asthma and tumor metastasis. The encoded protein may play an important role in embryogenesis, particularly in neuronal cells, as well as in lymphocyte development and survival. [provided by RefSeq, May 2013]
Chromosome	10
Cytoband	q26.2
Chromosome location (bp)	125766453 - 125775821
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000154485 (version 83.38)
Entrez gene	118856
UniProt	Q8N119 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8N119
Antibodypedia	MMP21 antibodies

PROTEIN BROWSER

MMP21-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MMP21-001 ENSP00000357798 ENST00000368808	Q8N119 [Direct mapping] Matrix metalloproteinase-21 Show all	Enzymes Peptidases Metallopeptidases Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Show all	GO:0002244 [hematopoietic progenitor cell differentiation] GO:0004222 [metalloendopeptidase activity] GO:0005509 [calcium ion binding] GO:0005576 [extracellular region] GO:0006508 [proteolysis] GO:0007368 [determination of left/right symmetry] GO:0008237 [metallopeptidase activity] GO:0008270 [zinc ion binding] GO:0031012 [extracellular matrix] GO:0060976 [coronary vasculature development] Show all	569 aa 65 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.