Cell atlas - APOOL - The Human Protein Atlas

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APOOL

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Mitochondria

Human cell
	Mitochondria

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GENERAL INFORMATION
Gene name	APOOL
Gene description	Apolipoprotein O-like
Protein class	Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the mitochondria.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Mitochondria (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA000612
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the mitochondria.

Main location

Mitochondria (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA000612	A-431	Mitochondria
	HPA000612	U-2 OS	Mitochondria
	HPA000612	U-251 MG	Mitochondria

GENE INFORMATION
Gene name	APOOL (HGNC Symbol)
Synonyms	AAIR8193, CXorf33, FAM121A, Mic27, UNQ8193
Description	Apolipoprotein O-like (HGNC Symbol)
Entrez gene summary	This gene encodes a protein which contains an apolipoprotein O superfamily domain. This domain is found on proteins in circulating lipoprotein complexes. [provided by RefSeq, Sep 2011]
Chromosome	X
Cytoband	q21.1
Chromosome location (bp)	85003826 - 85093316
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000155008 (version 83.38)
Entrez gene	139322
UniProt	Q6UXV4 (UniProt - Evidence at protein level)
neXtProt	NX_Q6UXV4
Antibodypedia	APOOL antibodies

PROTEIN BROWSER

APOOL-001	APOOL-201	APOOL-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
APOOL-001 ENSP00000362268 ENST00000373173	Q6UXV4 [Direct mapping] MICOS complex subunit MIC27 Show all	MEMSAT3 predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005739 [mitochondrion] GO:0005743 [mitochondrial inner membrane] GO:0061617 [MICOS complex] Show all	268 aa 29.2 kDa	Yes	0
APOOL-201 ENSP00000481770 ENST00000613473	A0A087WYF7 [Direct mapping] MICOS complex subunit MIC27 Show all	MEMSAT3 predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all		268 aa 29.2 kDa	Yes	0
APOOL-202 ENSP00000479012 ENST00000622540	A0A087WUX8 [Direct mapping] MICOS complex subunit MIC27 Show all	MEMSAT3 predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all		263 aa 28.8 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.