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CDK20

GENERAL INFORMATION

Gene name

 CDK20

Gene description

 Cyclin-dependent kinase 20

Protein class

 Enzymes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 5
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
GTEx:Mixed
FANTOM5:Mixed

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic and nuclear expression in most tissues. Expression in fallopian tube.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Pending external verification.

Reliability score

 Approved based on 3 antibodies.
HPA007666 , HPA027379 , HPA027401
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Fallopian tube

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed

GENE INFORMATION

Gene name

 CDK20 (HGNC Symbol)

Synonyms

 CCRK, p42

Description

 Cyclin-dependent kinase 20 (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene contains a kinase domain most closely related to the cyclin-dependent protein kinases. The encoded kinase may activate cyclin-dependent kinase 2 and is involved in cell growth. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Dec 2009]

Chromosome

 9

Cytoband

 q22.1

Chromosome location (bp)

 87966441 - 87974753

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000156345 (version 83.38)

Entrez gene

 23552

UniProt

 Q8IZL9 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8IZL9

Antibodypedia

 CDK20 antibodies

PROTEIN BROWSER
CDK20-001
CDK20-004
CDK20-005
CDK20-006
CDK20-012

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CDK20-001
ENSP00000365043
ENST00000375883
Q8IZL9 [Direct mapping]
Cyclin-dependent kinase 20
Show all
Enzymes
   ENZYME proteins
   Transferases
   Kinases
   CMGC Ser/Thr protein kinases
Predicted intracellular proteins
Show all
GO:0004672 [protein kinase activity]
GO:0004693 [cyclin-dependent protein serine/threonine kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005929 [cilium]
GO:0006468 [protein phosphorylation]
GO:0007049 [cell cycle]
GO:0007275 [multicellular organismal development]
GO:0051301 [cell division]
GO:0051726 [regulation of cell cycle]
Show all
 325 aa
36.1 kDa 		No 0
CDK20-004
ENSP00000322343
ENST00000325303
Q8IZL9 [Direct mapping]
Cyclin-dependent kinase 20
Show all
Enzymes
   ENZYME proteins
   Transferases
   Kinases
   CMGC Ser/Thr protein kinases
   MEMSAT-SVM predicted membrane proteins
Predicted intracellular proteins
Show all
GO:0004672 [protein kinase activity]
GO:0004693 [cyclin-dependent protein serine/threonine kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005929 [cilium]
GO:0006468 [protein phosphorylation]
GO:0007049 [cell cycle]
GO:0007275 [multicellular organismal development]
GO:0051301 [cell division]
GO:0051726 [regulation of cell cycle]
Show all
 346 aa
38.7 kDa 		No 0
CDK20-005
ENSP00000338975
ENST00000336654
Q8IZL9 [Direct mapping]
Cyclin-dependent kinase 20
Show all
Enzymes
   ENZYME proteins
   Transferases
   Kinases
   CMGC Ser/Thr protein kinases
Predicted intracellular proteins
Show all
GO:0004672 [protein kinase activity]
GO:0004693 [cyclin-dependent protein serine/threonine kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005929 [cilium]
GO:0006468 [protein phosphorylation]
GO:0007049 [cell cycle]
GO:0007275 [multicellular organismal development]
GO:0051301 [cell division]
GO:0051726 [regulation of cell cycle]
Show all
 338 aa
37.6 kDa 		No 0
CDK20-006
ENSP00000365031
ENST00000375871
Q8IZL9 [Direct mapping]
Cyclin-dependent kinase 20
Show all
Enzymes
   ENZYME proteins
   Transferases
   Kinases
   CMGC Ser/Thr protein kinases
Predicted intracellular proteins
Show all
GO:0004672 [protein kinase activity]
GO:0004693 [cyclin-dependent protein serine/threonine kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005929 [cilium]
GO:0006468 [protein phosphorylation]
GO:0007049 [cell cycle]
GO:0007275 [multicellular organismal development]
GO:0051301 [cell division]
GO:0051726 [regulation of cell cycle]
Show all
 243 aa
27.1 kDa 		No 0
CDK20-012
ENSP00000474485
ENST00000605159
Q8IZL9 [Direct mapping]
Cyclin-dependent kinase 20
Show all
Enzymes
   ENZYME proteins
   Transferases
   Kinases
   CMGC Ser/Thr protein kinases
Predicted intracellular proteins
Show all
GO:0004672 [protein kinase activity]
GO:0004693 [cyclin-dependent protein serine/threonine kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005929 [cilium]
GO:0006468 [protein phosphorylation]
GO:0007049 [cell cycle]
GO:0007275 [multicellular organismal development]
GO:0051301 [cell division]
GO:0051726 [regulation of cell cycle]
Show all
 275 aa
30.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.