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C2CD2

GENERAL INFORMATION

Gene name

 C2CD2

Gene description

 C2 calcium-dependent domain containing 2

Protein class

 Predicted intracellular proteins
Predicted secreted proteins

Predicted localization

 Intracellular,Secreted

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (adrenal gland)
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in several tissues, most abundant in adrenal gland.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Pending external verification.

Reliability score

 Approved based on 2 antibodies.
HPA030922 , HPA030924
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Adrenal gland

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (adrenal gland)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 C2CD2 (HGNC Symbol)

Synonyms

 C21orf25, C21orf258, DKFZP586F0422, TMEM24L

Description

 C2 calcium-dependent domain containing 2 (HGNC Symbol)

Entrez gene summary

Chromosome

 21

Cytoband

 q22.3

Chromosome location (bp)

 41885112 - 41953890

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000157617 (version 83.38)

Entrez gene

 25966

UniProt

 Q9Y426 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9Y426

Antibodypedia

 C2CD2 antibodies

PROTEIN BROWSER
C2CD2-001
C2CD2-002
C2CD2-006

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
C2CD2-001
ENSP00000369853
ENST00000380486
Q9Y426 [Direct mapping]
C2 domain-containing protein 2
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   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005576 [extracellular region]
GO:0005634 [nucleus]
GO:0005829 [cytosol]
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 696 aa
75.5 kDa 		Yes 0
C2CD2-002
ENSP00000329302
ENST00000329623
Q9Y426 [Direct mapping]
C2 domain-containing protein 2
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005576 [extracellular region]
GO:0005634 [nucleus]
GO:0005829 [cytosol]
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 541 aa
58.6 kDa 		No 0
C2CD2-006
ENSP00000388704
ENST00000449165
H7BZB0 [Direct mapping]
C2 domain-containing protein 2
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 182 aa
19.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.