Cell atlas - EXTL1 - The Human Protein Atlas

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EXTL1

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	EXTL1
Gene description	Exostosin-like glycosyltransferase 1
Protein class	Enzymes Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enriched (WM-115)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enriched (WM-115) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	EXTL1 (HGNC Symbol)
Synonyms	EXTL, MGC70794
Description	Exostosin-like glycosyltransferase 1 (HGNC Symbol)
Entrez gene summary	This gene is a member of the multiple exostoses (EXT) family of glycosyltransferases, which function in the chain polymerization of heparan sulfate and heparin. The encoded protein harbors alpha 1,4- N-acetylglucosaminyltransferase activity, and is involved in chain elongation of heparan sulfate and possibly heparin. [provided by RefSeq, Jul 2008]
Chromosome	1
Cytoband	p36.11
Chromosome location (bp)	26019884 - 26036464
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000158008 (version 83.38)
Entrez gene	2134
UniProt	Q92935 (UniProt - Evidence at transcript level)
neXtProt	NX_Q92935
Antibodypedia	EXTL1 antibodies

PROTEIN BROWSER

EXTL1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
EXTL1-001 ENSP00000363398 ENST00000374280	Q92935 [Direct mapping] Exostosin-like 1 Show all	Enzymes ENZYME proteins Transferases MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Show all	GO:0001501 [skeletal system development] GO:0005789 [endoplasmic reticulum membrane] GO:0006024 [glycosaminoglycan biosynthetic process] GO:0006486 [protein glycosylation] GO:0015012 [heparan sulfate proteoglycan biosynthetic process] GO:0016021 [integral component of membrane] GO:0050508 [glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity] Show all	676 aa 74.7 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.