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Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

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Searches

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Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

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UBXN11
  • TISSUE

  • CELL

  • PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

UBXN11

Gene description

UBX domain protein 11

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

12
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in most tissues.

DATA RELIABILITY

Data reliability
description

Antibody staining mainly not consistent with RNA expression data. Pending external verification.

Reliability score

Approved based on 1 antibody.
HPA028600
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Fallopian tube

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

UBXN11 (HGNC Symbol)

Synonyms

SOC, SOCI, UBXD5

Description

UBX domain protein 11 (HGNC Symbol)

Entrez gene summary

This gene encodes a protein with a divergent C-terminal UBX domain. The homologous protein in the rat interacts with members of the Rnd subfamily of Rho GTPases at the cell periphery through its C-terminal region. It also interacts with several heterotrimeric G proteins through their G-alpha subunits and promotes Rho GTPase activation. It is proposed to serve a bidirectional role in the promotion and inhibition of Rho activity through upstream signaling pathways. The 3' coding sequence of this gene contains a polymoprhic region of 24 nt tandem repeats. Several transcripts containing between 1.5 and five repeat units have been reported. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

p36.11

Chromosome location (bp)

26281328 - 26318363

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000158062 (version 83.38)

Entrez gene

91544

UniProt

Q5T124 (UniProt - Evidence at protein level)

neXtProt

NX_Q5T124

Antibodypedia

UBXN11 antibodies

PROTEIN BROWSER

«
UBXN11-001
UBXN11-002
UBXN11-003
UBXN11-004
UBXN11-008
UBXN11-009
UBXN11-010
UBXN11-011
UBXN11-014
UBXN11-015
UBXN11-016
UBXN11-201
»

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

UBXN11-001
ENSP00000363339
ENST00000374222
Q5T124 [Direct mapping]
UBX domain-containing protein 11
Show all
Predicted intracellular proteins
Show all
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005856 [cytoskeleton]
GO:0043130 [ubiquitin binding]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
Show all
520 aa
57.4 kDa
No 0
UBXN11-002
ENSP00000349601
ENST00000357089
Q5T124 [Direct mapping]
UBX domain-containing protein 11
Show all
Predicted intracellular proteins
Show all
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005856 [cytoskeleton]
GO:0043130 [ubiquitin binding]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
Show all
487 aa
54 kDa
No 0
UBXN11-003
ENSP00000324721
ENST00000314675
Q5T124 [Direct mapping]
UBX domain-containing protein 11
Show all
Predicted intracellular proteins
Show all
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005856 [cytoskeleton]
GO:0043130 [ubiquitin binding]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
Show all
400 aa
43.3 kDa
No 0
UBXN11-004
ENSP00000363338
ENST00000374221
Q5T124 [Direct mapping]
UBX domain-containing protein 11
Show all
Predicted intracellular proteins
Show all
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005856 [cytoskeleton]
GO:0043130 [ubiquitin binding]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
Show all
520 aa
57.4 kDa
No 0
UBXN11-008
ENSP00000363340
ENST00000374223
X6R8M6 [Direct mapping]
UBX domain-containing protein 11
Show all
Predicted intracellular proteins
Show all
GO:0005515 [protein binding]
GO:0043130 [ubiquitin binding]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
Show all
277 aa
30.1 kDa
No 0
UBXN11-009
ENSP00000413448
ENST00000450041
Q5T118 [Direct mapping]
UBX domain-containing protein 11
Show all
Predicted intracellular proteins
Show all
GO:0043130 [ubiquitin binding]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
Show all
116 aa
13.7 kDa
No 0
UBXN11-010
ENSP00000395165
ENST00000421827
X6RDY0 [Direct mapping]
UBX domain-containing protein 11
Show all
Predicted intracellular proteins
Show all
GO:0043130 [ubiquitin binding]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
Show all
134 aa
14.8 kDa
No 0
UBXN11-011
ENSP00000404956
ENST00000442942
Q5T130 [Direct mapping]
UBX domain-containing protein 11
Show all
Predicted intracellular proteins
Show all
GO:0043130 [ubiquitin binding]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
Show all
185 aa
21.1 kDa
No 0
UBXN11-014
ENSP00000363332
ENST00000374215
X6R8K8 [Direct mapping]
UBX domain-containing protein 11
Show all
Predicted intracellular proteins
Show all
GO:0043130 [ubiquitin binding]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
Show all
247 aa
28 kDa
No 0
UBXN11-015
ENSP00000410357
ENST00000452980
X6RIY5 [Direct mapping]
UBX domain-containing protein 11
Show all
Predicted intracellular proteins
Show all
GO:0043130 [ubiquitin binding]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
Show all
207 aa
23.6 kDa
No 0
UBXN11-016
ENSP00000394036
ENST00000423664
X6RDK7 [Direct mapping]
UBX domain-containing protein 11
Show all
Predicted intracellular proteins
Show all
GO:0043130 [ubiquitin binding]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
Show all
148 aa
16.9 kDa
No 0
UBXN11-201
ENSP00000363334
ENST00000374217
Q5T124 [Direct mapping]
UBX domain-containing protein 11
Show all
Predicted intracellular proteins
Show all
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005856 [cytoskeleton]
GO:0043130 [ubiquitin binding]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
Show all
487 aa
54 kDa
No 0

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.