Tissue expression of PKD1L1 - Summary - The Human Protein Atlas

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PKD1L1

TISSUE

CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	PKD1L1
Gene description	Polycystic kidney disease 1 like 1
Protein class	Plasma proteins Predicted membrane proteins Transporters
Predicted localization	Membrane
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (testis)
GTEx:	Mixed
FANTOM5:	Tissue enhanced (lung, retina)

Protein evidence

Evidence at protein level

Protein expression

Estimation of protein expression could not be performed. View primary data.

DATA RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 2 antibodies. HPA020422 , HPA022424
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

N/A

Caudate

N/A

N/A

Cerebellum

N/A

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

N/A

Bronchus

N/A

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

N/A

Skin

N/A

Skin

N/A

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (testis)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Mixed
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (lung, retina)

GENE INFORMATION
Gene name	PKD1L1 (HGNC Symbol)
Synonyms	PRO19563
Description	Polycystic kidney disease 1 like 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the polycystin protein family containing 11 transmembrane domains, a receptor for egg jelly (REJ) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. The encoded protein may play a role in the male reproductive system. Alternative splice variants have been described but their biological nature has not been determined. [provided by RefSeq, Jul 2008]
Chromosome	7
Cytoband	p12.3
Chromosome location (bp)	47774652 - 47948491
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000158683 (version 83.38)
Entrez gene	168507
UniProt	Q8TDX9 (UniProt - Evidence at protein level)
neXtProt	NX_Q8TDX9
Antibodypedia	PKD1L1 antibodies

PROTEIN BROWSER

PKD1L1-001	PKD1L1-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PKD1L1-001 ENSP00000289672 ENST00000289672	Q8TDX9 [Direct mapping] Polycystic kidney disease protein 1-like 1 Show all	Transporters Transporter channels and pores Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins Protein evidence (Kim et al 2014) Show all	GO:0003127 [detection of nodal flow] GO:0005262 [calcium channel activity] GO:0005515 [protein binding] GO:0005929 [cilium] GO:0007368 [determination of left/right symmetry] GO:0007507 [heart development] GO:0016020 [membrane] GO:0016337 [single organismal cell-cell adhesion] GO:0031513 [nonmotile primary cilium] GO:0034704 [calcium channel complex] GO:0050982 [detection of mechanical stimulus] GO:0060170 [ciliary membrane] GO:0060972 [left/right pattern formation] GO:0070588 [calcium ion transmembrane transport] GO:0070986 [left/right axis specification] Show all	2849 aa 315.4 kDa	No	>9
PKD1L1-002 ENSP00000393466 ENST00000433506	H7C083 [Direct mapping] Polycystic kidney disease protein 1-like 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] GO:0050982 [detection of mechanical stimulus] Show all	164 aa 18.3 kDa	No	1

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.