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Mospt malignant cells showed moderate to strong cytolasmic and rare nuclear staining. Several renal cancers were weakly stained or negative.
GENE INFORMATION
Gene name
PINK1 (HGNC Symbol)
Synonyms
PARK6
Description
PTEN induced putative kinase 1 (HGNC Symbol)
Entrez gene summary
This gene encodes a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease. [provided by RefSeq, Jul 2008]